Editors: Raja Chakraborty, Saikat Sen

Series Title: Natural Medicine

New Avenues in Drug Discovery and Bioactive Natural Products

Volume 2

eBook: US $69 Special Offer (PDF + Printed Copy): US $110
Printed Copy: US $76
Library License: US $276
ISSN: 2972-4694 (Print)
ISSN: 2972-4686 (Online)
ISBN: 978-981-5136-33-3 (Print)
ISBN: 978-981-5136-32-6 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151363261230201

Introduction

New Avenues in Drug Discovery and Bioactive Natural Products is the second volume of the Natural Medicine book series. It is devoted to current research in drug discovery from natural sources.The volume features 13 chapters that cover modern analytical and scientific approaches. The book starts with chapters on advanced analytical and research techniques, such as genomic mining, quality control of herbal drugs, DNA fingerprinting, high-throughput screening, molecular docking and extraction techniques. The contributors provide a summary of challenges for researchers and commercial applications where possible. The book also features chapters dedicated to specific medicinal agents that target a disease glycosides, SARS-CoV2 spike protein inhibitors, and andrographolides.

The collection of important research topics in natural product chemistry aims to help the scholars and researchers in the scientific community that are involved in the extraction and development of new medicines.

Audience

Postgraduate researchers and students in phytochemistry, medicinal chemistry, herbal medicine, biochemistry and pharmacology.

Preface

Natural products always play an important role in the process of drug discovery and the development of modern medicine. Drug discovery aiming to find robust and viable lead candidates is a challenging and time taking process that involves the participation of experts from various fields. Screening of natural products to a new molecule or new biological effect of an existing drug candidate requires expertise, experience and modern techniques. Natural products and their structural analogues are used as a lead in the drug discovery process and have always played an imperative role in pharmacotherapy. However, drug discovery from natural products is always challenging because of technical issues, such as screening, isolation, characterization, identification and optimization, which results in a decline in their pursuit by pharmaceutical companies. Over the past few decades, the demand for natural products has been increasing, and researchers have concentrated on drug discovery from natural sources, predominantly focusing on traditional medicinal information. Plants are an abundant source of chemically vastly diverse secondary metabolites, which upon screening, exhibited different biological functions and are still far from being comprehensively investigated. Scientific awareness in natural product-based drug discovery leads to concentrating the focus on finding a new strategy for isolation, identification, characterization, screening of natural products and resupply of biologically active compounds being developed, which are the necessity of the future. Drug discovery from medicinal plants can be considered a hot spot of research. A large number of drugs were obtained from the medicinal plant, and several others have been discovered by using phytochemicals as lead. Plants have historically proven their value as a major source of bioactive molecules, and still represent an imperative tool for the discovery of novel drug leads. Intrinsic complexity involved in drug discovery from plant sources necessitates extremely integrated interdisciplinary approaches. Scientific developments and technological advancement, including sophisticated analytical tools, engineering strategies, in silico approach, etc., are opening up new opportunities to reestablish natural products as a key source for drug discovery and find new drugs quickly. Volume 2 of this series of the book entitled “Natural Medicine: New Avenues in Drug Discovery and Bioactive Natural Products” is devoted to the current research in drug discovery from natural sources, modern analytical and scientific approaches, the bioactivity of isolated phytochemicals and their analogues. This volume is a collection of important research on this field which will strengthen scientific advancement on natural product-based drug discovery and will be helpful for the scientific community.

Raja Chakraborty
Institute of Pharmacy
Assam Don Bosco University
Tapesia Gardens
Sonapur – 782 402
Assam India


Saikat Sen
Faculty of Pharmaceutical Science
Assam Downtown University
Panikhiti, Guwahati - 781026
Assam India

RELATED BOOKS

.Medicinal Chemistry of Drugs Affecting Cardiovascular and Endocrine Systems.
.Software and Programming Tools in Pharmaceutical Research.
.Objective Pharmaceutics: A Comprehensive Compilation of Questions and Answers for Pharmaceutics Exam Prep.
.Marine Biopharmaceuticals: Scope and Prospects.