Editors: Reza Heidari, M. Mehdi Ommati

Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases

eBook: US $79 Special Offer (PDF + Printed Copy): US $127
Printed Copy: US $87
Library License: US $316
ISBN: 978-981-5124-49-1 (Print)
ISBN: 978-981-5124-48-4 (Online)
Year of Publication: 2023


Taurine, or 2-aminoethanesulfonic acid, is one of the most abundant sulfur-containing amino acids in the human body. It is found in the heart, brain, retina, and skeletal muscles, and is synthesized in the pancreas. Studies have revealed that taurine is of high physiological importance: it protects against pathologies associated with mitochondrial diseases, and linked processes like aging, metabolic syndrome, cancer, cardiovascular diseases, and neurological disorders. It is also used as a nutritional supplement.

Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases explores the significance of taurine in the biology of mitochondria. It also explains its role as a pharmacological agent for treating different diseases. Readers will gain an insight into the crucial role it plays in human physiology and the benefits of taurine supplements.

Topics covered in this reference include

- Synthesis of taurine and its dietary sources

- The Role of taurine in mitochondrial health

- Taurine as a neurotransmitter

- Beneficial effects of taurine in physiological systems such as the reproductive system, renal system, and the gastrointestinal tract

- Hepatoprotective and anti-inflammatory properties of taurine

- The anti-aging promise of taurine supplementation

- Role of taurine supplementation in obesity


The use of safe molecules for treating diseases has always been of special interest in medical sciences. During research on the application of potential drug candidates for the treatment and prevention of human disease, the application of the amino acid taurine received attention from the authors. The use of the amino acid taurine in the treatment of human diseases has also attracted the attention of many researchers in various fields of biomedical sciences. Numerous studies revealed that taurine could treat and prevent a wide range of diseases by affecting the fundamental signaling pathways and cellular function. The effect of taurine on mitochondria is one of this substance's key mechanisms in preventing cell damage. In the present book, the effects of taurine on mitochondria and its relationship with the treatment of various human diseases have been given special attention and widely discussed. Researchers in biomedical sciences could widely use the data provided in this book. We hope that attention to compounds such as the amino acid taurine, a safe molecule that causes no significant side effects even at very high doses, can lead to the development of new and effective strategies in the pharmacotherapy of various human diseases.


Not applicable.


The author declares no conflict of interest, financial or otherwise.


The current study was financially supported by the Vice-Chancellor of Research Affairs, Shiraz University of Medical Sciences, Shiraz, Iran (Grants: 12203/12028/11738/ 12806/12243/23158/23024/16259/13555).

Reza Heidari
Pharmaceutical Sciences Research Center
Shiraz University of Medical Sciences
Shiraz, Iran


Mohammad Mehdi Ommati
Henan Key Laboratory of Environmental and Animal Product Safety
College of Animal Science and Technology
Henan University of Science and Technology
Luoyang 471000, Henan, China

The authors contributed equally to this book