Author: Seyed Morteza Naghib

Electrochemical Biosensors in Practice: Materials and Methods

eBook: US $49 Special Offer (PDF + Printed Copy): US $78
Printed Copy: US $54
Library License: US $196
ISBN: 978-981-5123-95-1 (Print)
ISBN: 978-981-5123-94-4 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151239441230101


A biosensor is an integrated receptor-transducer device that converts a biological response into an electrical signal. The design and development of biosensors have taken center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications in healthcare and disease diagnosis, environmental monitoring, water and food quality, and drug delivery. Due to their adaptability, ease of use in relatively complex samples, and portability, the significance of electrochemical biosensors in analytical chemistry has increased manifold. Electrochemistry has been pivotal in developing transduction methods for biological processes and biosensors. In parallel, the explosion of activity in nanoscience and nanotechnology and their huge success have profoundly affected biosensor technology, opening new avenues of research for electrode materials and transduction.

Electrochemical Biosensors in Practice: Material and Methods particularly explores the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Therefore, the book serves as an introductory text for those specializing in biosensors and bioelectronics and their practical applications.

Key features

- Includes structured information for easy understanding of the subject

- Provides an introduction to biosensors and electrochemical biosensor classification

- Explains fundamental concepts and practical electrochemistry techniques for research

- Provides notes on essential electrochemical sensor materials such as graphene, carbon nanotubes, conductive polymers, and other advanced materials

- Provides information about electrochemical biosensor development

- Informs readers about recent applications and research findings

- Includes references for further reading


Students in chemistry, biomedical engineering and advanced engineering course


Since Clark's first invention of biosensors in 1956, various enhancements have been made, and new detection methods have been proposed for their future development. The term “biosensor” refers to any analytical instrument that detects an analyte using a bioreceptor and a transducer in addition to a physicochemical detector. They exhibit a high degree of selectivity due to the interactions between the bioreceptors' structure and the analyte (biorecognition). Due to their unique interaction, biosensor signals cannot be tampered with by other substances. Numerous biorecognition molecules, including aptamers and antibodies as well as enzymes and nucleic acids, have been employed in the creation of biosensors because of new technology in electronics and microprocessors. Because of these changes, biosensors can now be put on a smaller surface.

Electrochemistry is a common technique of signal transduction in biosensors. It includes electrochemiluminescence, potentiometry, impedance spectroscopy, amperometry, conductometry and voltammetry. Recent advancements in nanotechnology and nanoscience have enabled biosensor researchers to conduct ground-breaking research into novel biomaterials and materials with superior physical, biocompatible, mechanical and electrical properties, paving the way for manufacturing of even more efficient electrodes. Innovative electrochemical biosensors are finding new applications as a consequence of this study. Nanostructured biomaterials are one of the most versatile forms of biomaterials since they may be utilized to produce electrodes with micrometer-sized surface areas. For instance, carbon nanotubes and quantum dots, which are used in biosensors, display hitherto unseen properties. As a result, biosensors have become a strong and interesting field thanks to the development of small electrodes that can detect even the smallest amounts of analytes in living systems.

As a result of these advancements, this book will present an overview of electrochemical biosensors, covering the many types and surface modification methods that are now available. The subjects explored in this book will pique the curiosity of a wide variety of readers. This category of nanomaterial-based systems includes carbon nanomaterials and biosensor signal monitoring devices. Electrochemical biosensors based on microbial cells, nucleic acids, aptamers, and enzymes, as well as receptor-based biosensors for metabolite detection and physiological process research, highlight how electrochemistry may be utilized for metabolite detection and physiological process research. If you are a student or a scientist, this book will help you. It includes contributions from well-known experts in the field of electrochemical transduction for biosensors.


Not applicable.


The authors declare no conflict of interest, financial or otherwise.


Declared none.

Seyed Morteza Naghib

Seyed Mahdi Katebi


Sadegh Ghorbanzade

Nanotechnology Department
School of Advanced Technologies
Iran University of Science and Technology (IUST)