Foreword

Natural products are continually attracting researchers, and gaining popularity all over the globe as other alternative drug discovery methods are failing to provide a satisfactory number of novel lead compounds which can qualify as drugs against various diseases. The Himalayas are noted for their vast plant richness, as well as their abundance of bioactive phytoconstituents due to their extreme ecological circumstances. In folklore and traditional medicine, a variety of Himalayan-based plants are employed for their medicinal use. There are growing experimental studies that substantiate the pharmacological potential of various phytochemicals of Himalayan-origin. This book will serve as an important literature discovery tool for researchers engaged in drug discovery using plant medicines. This book compiled the experimental evidence that implicates the role and effectiveness of bioactive phytochemicals derived from these valuable plants for the treatment and management of various diseases. The book has been divided into 11 chapters that explore the pharmacological properties of Himalayan plants in the management of cancer, hepatic diseases, diabetes, neurodegenerative, inflammatory diseases, etc. A special account of bioactive properties of various Himalayan plants such as Grewia sp., Atropa belladonna, Tinospora cordifolia, Swertia and chirayita, against various diseases has also been given in the book. This book also covers two methodological chapters. One of the chapters gives an account of phytochemical databases and the other chapter guides through some of the tools and procedures for isolating phytochemicals from Himalayan plants. This unique compilation will serve as a reference guide for academicians, researchers, and students interested in exploring various therapeutic aspects of Himalayan plants.