Editors: Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)

eBook: US $59 Special Offer (PDF + Printed Copy): US $101
Printed Copy: US $71
Library License: US $236
ISBN: 978-981-5123-11-1 (Print)
ISBN: 978-981-5123-10-4 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151231041230101

Introduction

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing.

Topics included in the book include:

- the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix.

- fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation

- the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential.

- strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration.

- the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use

Part 1 covers techniques for tissue engineering, wound healing and skin engineering. It also presents reviews on techniques such as acellular synthesis and 3D bioprinting. Materials highlighted in this part include chitosan-based nanoparticles, nanocollagen-based materials and plant based composites.

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Audience

Researchers in biomedical engineering, biomedicine, pharmacology and nanomedicine

Preface

The regenerative medicine is currently an established technology, covering tissue engineering as a significant field in various health applications. Traditionally, tissue engineering is a combination of cells, biomaterials, and biomolecules to replace or repair damaged tissues. The current advanced technology in the tissue engineering field focuses on the functionalisation of invented bio-based materials. It includes the development of a hybrid or composite biomatrix together with cells-secreted products and related active compounds for better performance in enhancing the rapid therapeutic mechanism. The mode of action for the invented product depends on its formulation or a three-dimensional design of the biomatrix.

This book provides detailed information on the latest advancements in bio-based materials treatment strategy for various tissue applications, encompassing skin, bone, heart, respiratory tract and other vital organs. This is followed by future perspectives on the new emerging treatment in the field of tissue engineering and regenerative medicine.

Mohd Fauzi Mh Busra
Centre for Tissue Engineering and Regenerative Medicine (CTERM),
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif,
Bandar Tun Razak, 56000 Cheras,
Kuala Lumpur,
Malaysia


Daniel Law Jia Xian
Centre for Tissue Engineering and Regenerative Medicine (CTERM),
Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000 Cheras,
Kuala Lumpur,
Malaysia


Yogeswaran Lokanathan
Centre for Tissue Engineering and Regenerative Medicine (CTERM),
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif,
Bandar Tun Razak, 56000 Cheras,
Kuala Lumpur,
Malaysia


&

Ruszymah Haji Idrus
Centre for Tissue Engineering and Regenerative Medicine (CTERM),
Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras,
Kuala Lumpur,
Malaysia