Editors: Arumugam Veera Ravi, Ramanathan Srinivasan, Arunachalam Kannappan

Series Title: Frontiers in Antimicrobial Agents

Recent Advances in the Application of Marine Natural Products as Antimicrobial Agents

Volume 3

eBook: US $79 Special Offer (PDF + Printed Copy): US $136
Printed Copy: US $96
Library License: US $316
ISSN: 2452-2570 (Print)
ISSN: 2452-2589 (Online)
ISBN: 978-981-5080-15-5 (Print)
ISBN: 978-981-5080-14-8 (Online)
Year of Publication: 2023
DOI: 10.2174/97898150801481230301

Introduction

While the world is grappling with the growing problem of antibiotic resistance, marine organisms offer a promising solution with their diverse repertoire of bioactive compounds. This thematic volume explores the untapped potential of marine organisms in the fight against microbial threats. The focus of the 17 featured chapters lies in highlighting the vast array of antimicrobial agents that can be found within marine environments. The chapters provide in-depth knowledge about the latest discoveries, advancements and future needs in antimicrobial research. Readers will learn about astonishing discoveries of natural compounds with remarkable antimicrobial properties and sources. The list of agents covered in the book includes synthetic derivatives, bioactive polysaccharides and marine viruses. The book also includes chapters that cover various stages of the antimicrobial drug development process, providing an overview of recent antimicrobial agents derived from marine organisms, preclinical studies and the identification of patented drugs sourced from the ocean. Furthermore, the book sheds light on the diverse applications of these marine-derived compounds, spanning the fields of medicine, agriculture, and industry.

Professionals in the fields of microbiology, marine biology, pharmaceutical sciences, and drug development will gain valuable insights into the use of marine organisms as a source of antimicrobial agents.

Audience: Medicinal chemists, professional researchers and scholars in microbiology, marine biology and related fields in life sciences.

Foreword

- Pp. i
Ariel Kushmaro
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Preface

- Pp. ii-iii (2)
Arumugam Veera Ravi, Ramanathan Srinivasan, Arunachalam Kannappan
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List of Contributors

- Pp. iv-viii (5)

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Antimicrobial Drug Discovery Approaches, Challenges, and Development

- Pp. 1-44 (44)
Murugesan Sivaranjani, Aaron P. White*

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Marine Natural Products as Tools for Discovering New Antimicrobial Targets

- Pp. 45-64 (20)
Issac Abraham Sybiya Vasantha Packiavathy*, Danaraj Jeyapragash, Dharmadhas Jeba Sweetly, Arumugam Veera Ravi

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An Overview of the Antimicrobials from Marine Bacteria

- Pp. 65-86 (22)
Ramanathan Srinivasan, Arunachalam Kannappan, Xiaomeng Chen, Chunlei Shi, Xiangmin Lin*

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Marine Bacterial Viruses: The Inevitable Natural Antimicrobial Agents in the Marine Environment

- Pp. 87-105 (19)
Anandababu Philomena Joy Lindsey, Robinson Emilin Renitta, Sevanan Murugan*

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Marine Cyanobacteria: Sustainable Resource for Vibrant Antimicrobial Agents

- Pp. 106-130 (25)
Sivasubramanian Santhakumari, Pandurangan Poonguzhali, Abimannan Arulkumar, Prathapkumar Halady Shetty, Madhu Dyavaiah*

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Reconnoitering Cell Factories of Marine Algae for Antimicrobials

- Pp. 131-146 (16)
Jibu Thomas*, S. Jerusha Pealin Grace

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Antimicrobials from Mangroves

- Pp. 147-170 (24)
Angusamy Annapoorani, Arumugam Veera Ravi, Sundaram Janarthanan, Kandasamy Kathiresan*

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A Recent Update on Sponge Bioprospecting and its Antimicrobial Properties: Their Biological Mode of Action

- Pp. 171-200 (30)
Balraj Sudha, Kanagaraj Suganya, Bishwambhar Mishra, Govindugari Vijaya Laxmi, Sanjeeb Kumar Mandal*, Sanjay Kumar, Sundaravadivelu Sumathi

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Antimicrobial Peptides: A Recent Update in the Pros, Cons, and Opportunities as Potential Antimicrobial Agents from Marine Resources

- Pp. 201-227 (27)
Arunachalam Kannappan*, Ramanathan Srinivasan, Sethuraman Sathya, Chunlei Shi*

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Antimicrobial Peptides from Marine Invertebrates

- Pp. 228-256 (29)
Srichandan Rath, Subhashree Jena, Sankar Kanchana, Muthuvel Arumugam*

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Marine Biosurfactants as Potential Agents to Combat Multi-Drug Resistant Pathogens

- Pp. 257-277 (21)
Pandi Saravana Kumari, Sevanan Murugan*

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Bioactive Polysaccharides with Antimicrobial Proficiency from Marine Environment

- Pp. 278-303 (26)
Arumugam Priya, Nagaiah Hari Prasath, Shunmugiah Karutha Pandian*

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Synthetic Derivatives from Marine Natural Products as Potential Antimicrobial Drugs

- Pp. 304-321 (18)
Ravindran Durgadevi, Arumugam Veera Veera Ravi*

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Marine Metabolites: An Untapped Resource for Combinatorial Approaches against Antimicrobial Resistance

- Pp. 322-344 (23)
Loganathan Vigneshwari, Arumugam Priya, Sivasamy Sethupathy*

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Nanomedicine from Seaweed and its Sulfated Polysaccharide Mediated Silver Nanoparticles for Microbial Disease Control

- Pp. 345-368 (24)
Ravichandran Anjali, Subramanian Palanisamy, Avudaiyan Muthamil Selvi, Manoharn Vinosha, Muthushanmugam Manikandakrishnan, Periyannan Rajasekar, Sonaimuthu Mohandoss, SangGuan You, Narayanasamy Marimuthu Prabhu*

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Preclinical Drug Entities in Clinical Trial Pipeline from Marine Source

- Pp. 369-388 (20)
Suganya Kannan*, Karvannan Sevugamurthi, Jeyakumar Balakrishnan, Ambujam Govindasamy, Murugan Marudhamuthu

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Recent Update on the Patents of Antimicrobial Marine Natural Products

- Pp. 389-408 (20)
Alwar Ramanujam Padmavathi*, Dhamodharan Bakkiyaraj, Sathya Narayanan Gokul

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Subject Index

- Pp. 409-414 (6)
Arumugam Veera Ravi, Ramanathan Srinivasan, Arunachalam Kannappan
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