Preface

Pyrazole is one of the most valuable nitrogen-based heterocycles and is incorporated in the constitution of a wide range of pharmaceuticals and agrochemicals. Direct connection of two pyrazole units produces six different bipyrazole skeletons that can be classified as i) N-N bond connected 1,1`-bipyrazoles; ii) C-N bond connected 1,3`- and 1,4`-bipyrazoles and iii) C-C bond connected 3,3`-, 3,4`- and 4,4`-bipyrazoles.

This book presents the recent achievements in the synthetic platforms toward the directly connected bipyrazole systems and their applications in academic, industrial, and material science fields. The construction of the targeted bipyrazole heterocycles was carried out via a wide-range of synthetic routes that grasp the attention of graduate and postgraduate chemists and pharmacists and material science researchers to make more efforts in this area to reach high impact findings for their applications in our life.

Most of the reported bipyrazoles are highly bioactive heterocycles demonstrating a broad array of significant inhibitory activities against several human diseases and agricultural pesticides and herbicides. They also have considerable applications in the material science area via involvement in the construction of metal-organic frameworks (MOFs) with distinguished industrial applications.

This book is presented in five chapters describing the synthesis of six connected bipyrazole systems and their brilliant and vibrant applications. As a result, we expect that the provided book chapters will be of pronounced support and a valuable source for the scientific community for developing new bipyrazole-based fascinating candidates towards optimization of their pharmacological benefits in the treatment of diseases as well as building up new MOFs for daily life applications that serve the humanity and industry.

We hope that the researchers and readers will find new ideas based on the provided work. Finally, we are very thankful to the Bentham Science Publishers for giving us the chance to publish this book.