Authors: Seyed Morteza Naghib, Samin Hoseinpour, Shadi Zarshad

Localized Micro/Nanocarriers for Programmed and On-Demand Controlled Drug Release

eBook: US $69 Special Offer (PDF + Printed Copy): US $110
Printed Copy: US $76
Library License: US $276
ISBN: 978-981-5051-64-3 (Print)
ISBN: 978-981-5051-63-6 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150516361220101


This book provides a comprehensive overview of the localized drug delivery system landscape. The 10 chapters provide a detailed introduction in polymers, nanostructures and nanocomposites for developing localized controlled drug delivery systems (LCDDSs) in the form of stimuli-responsive delivery systems, targeted drug delivery systems or the combination of both. A discussion on manufacturing techniques, optimization, challenges and adaptation of LCDDSs for the treatment of a wide range of diseases is also included.

This simple and informative resource conveys an understanding about designing novel drug delivery systems to students in advanced pharmacology, biotechnology, materials science and biochemistry study programs. Readers will be equipped with the knowledge of regulating drug release rates to get a desired pharmacological profile, that helps a researcher to ensure a high therapeutic effectiveness.

The detailed information about various drug delivery systems and a compilation of recent literature sources also paves the way for research scholars to construct a drug targeting framework for their research plans.

Audience: Pharmaceutical chemists, R&D researchers and advanced students of pharmacology, biotechnology, materials science and biochemistry


In the healthcare field, providing optimal treatment to individual patients is of primary concern. Drug delivery systems can regulate drug release rate to get the desired profile, ensure high therapeutic effectiveness, and reduce side effects that are very interesting in pharmaceutical and biomedical applications. The localized drug delivery presents various factors designed to enable the delivery of therapeutic agents, such as drugs, genes, proteins, etc., directly to the site of disease in a controlled manner, sparing off-target cell/tissue toxicities. In this context, one of the considerable challenges in systemic drug delivery systems is to get the desired drug concentration at the specific organ, reduce side effects, and prevent drug inefficiency. The present book entitled "smart stimuli-responsive micro/nanocarriers for programmed and on-demand localized controlled drug release" is one of the first books on the market that focuses on localized drug delivery with enhanced drug release at the target site, reduced local toxicity, and better patient compliance in order to inspire readers to design and create novel drug delivery systems for the treatment of a wide range of diseases.

In this book, the present chapters provide a detailed introduction to polymers, nanostructures, and stimuli-responsive materials and their great potential for opening new avenues to address several challenges in conventional dosage forms in localized drug delivery systems. This book is ideally designed for researchers working in pharmaceuticals, bionanotechnologies, biomedical engineering, materials science, and related industries.


Not applicable.


The author declares no conflict of interest, financial or otherwise.


Declared none.

Seyed Morteza Naghib
Nanotechnology Department, School of Advanced Technologies
Iran University of Science and Technology (IUST)
P.O. Box 16846-13114, Tehran