Editors: Fahima Dilnawaz, Ajit Kumar Behura

Artificial Intelligence Based Cancer Nanomedicine: Diagnostics, Therapeutics and Bioethics

eBook: US $39 Special Offer (PDF + Printed Copy): US $72
Printed Copy: US $52
Library License: US $156
ISBN: 978-981-5050-57-8 (Print)
ISBN: 978-981-5050-56-1 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150505611220101

Introduction

Nanomedicine is evolving with novel drug formulations devised for multifunctional approaches towards diagnostics ad therapeutics. Nanomedicine-based drug therapy is normally explored at a fixed dose. The drug action is time-dependent, dose-dependent and patient-specific. To overcome challenges of nanomedicine testing, artificial intelligence (AI) serves as a helping tool for optimizing the drug and dose parameters. Real time conversions between these two features enables upgradation of patient data acquisition and improved design of nanomaterials. In this scenario, AI-based pattern analysis and algorithms models can greatly improve accuracy of diagnostics and therapeutics.

This book gives a comprehensive explanation of the role of machine learning and artificial intelligence in cancer nanomedicine. It presents 10 chapters that cover multiple dimensions of the subject. These dimensions are:

- The need of AI and ML in designing new cancer drugs

- Application of AI in cancer drug design

- AI-based drug delivery models for cancer drugs

- Diagnostic applications of AI

- Intelligent nanosensors for biomarker profiling

- Predictive models for metastatic cancer

- Cancer nanotheranostics

- Ethics of AI in medicine

Contributions have been made by 16 researchers who are experts in pharmacology and drug design. The contents of the book bridge knowledge gaps between the fields of biomedical engineering, pharmacology and clinical medicine, with a focus on cancer treatment.

The book serves as a reference for scholars learning about cancer diagnostics and therapeutics. Biomedical engineers who are involved in healthcare projects will also find the concepts and techniques highlighted in the book informative for understanding modern computer-based approaches used to solve clinical problems.

Foreword

It give me immense pleasure to write the foreword of the e-book “Artificial Intelligence Based Cancer Nanomedicine: Diagnostics, Therapeutics and Bioethics” by Dr Fahima Dilnawaz and Dr Ajit Kumar Behura. This book offers an all-inclusive upcoming aspects of the recent development of artificial intelligence (AI) and nanotechnology in one of worst medical challenges of modern age, cancer treatment, diagnostics. The devastating global casualty to the tune of 10 million deaths per year in 2020 is no less alarming. The authors took an initiative to address this gigantic problem through the use of AI and nanomedicine. The amalgamation of AI and nanotechnology enables in realization of the goal of precision medicine for cancer patients. The field of nanomedicine has made significant strides in the areas of cancer therapeutics and diagnostic development. Although, nanomedicine has provided tremendous improvement over conventional cancer treatment, this new avenue needs continuous improvement. Nanomedicine-based drug delivery is often uses an approach of fixed dose and repeated administration of fixed doses as the case demands. It gives a persistent challenge as drug synergy is time-dependent, dose-dependent and patient-specific at any given point of treatment. In the field of nano-informatics, machine learning (ML) and AI and artificial neural network (ANN) and many computational models have been used in diverse fields of medical imaging and therapeutics to process large datasets and recognize complex patterns for improved design of nanotechnologies for diagnostics and treatment. Particularly in cancer, the high intra-tumor and inter-patient heterogeneities pose difficulty for the rational design of diagnosis and therapeutic platform. In this regard, the integration of AI with cancer nanomedicine can bridge the gap, through the pattern analysis and classification of algorithms for improved diagnostic and therapeutic accuracy.

This up-to-date book incorporates the advancement of AI and nanotechnology-based cancer nanomedicine in a comprehensive manner for the next generation of disease treatment. This book gives a in-depth information regarding cancer drug designing, diagnostics, drug-modeling, prediction modeling, nano-sensors, theranostics, and bioethics. The book delivers the texts in lucid language with suitable pictorial presentations of different concepts that will help the reader a better understanding of the subject. I am convinced that Dr. Fahima Dilnawaz and Dr. Ajit Kumar Behura have done a focused, detailed work in compiling and editing this cutting edge comprehensive E-book on AI-based cancer nanomedicine and emerging bioethical principle, written by experts, researchers and academicians. I wish this noteworthy and extraordinary compilation of scientific articles will undoubtedly bring additional wealth of information and knowledge to a cross disciplinary readership from the field of medicine, pharmaceutical science, social and legal expertise, and basic science. This book will have an innovative and thought provoking effect in the modern medical biology.

Prof. A.N. Misra
Distinguished Professor
Centurion University of Technology & Management, Bhubaneswar,Odisha
Former Vice Chancellor, Khalikote University (State), Odisha
Vice Chancellor (Actg), Central University of Jharkhand


Former Professor
Life Sciences, Central University of Jharkhand
Biosciences & Biotechnology, Fakir Mohan University, Balasore, Odisha
Botany, Utkal University, Odisha and Pune University, Maharastra