Editor: Abid Hussain Banday

Steroids and their Medicinal Potential

eBook: US $69 Special Offer (PDF + Printed Copy): US $119
Printed Copy: US $84
Library License: US $276
ISBN: 978-981-5049-34-3 (Print)
ISBN: 978-981-5049-33-6 (Online)
Year of Publication: 2023
DOI: 10.2174/97898150493361230101

Introduction

Steroids are an important class of biomolecules with diverse roles and functions. Besides being important as structural and signaling molecules, these molecules hold promise against numerous disorders, including cardiovascular conditions, cancer, inflammation and autoimmune disorders. Many investigations have demonstrated that steroidal frameworks may provide lipid solubility, receptor selectivity or membrane binding properties to non-steroidal pharmacophores. However, the therapeutic use of steroids can be dangerous when they're used incorrectly. Additionally, misconceptions about steroids among athletes or recreational users can lead to steroid abuse and poor health outcomes.

Steroids and their Medicinal Potential discusses the classification, distribution, biosynthesis, chemical synthesis and semi-synthesis of different steroids. The medicinal potential of each class is exhaustively discussed in different chapters. The latest advances and developments in steroid-based drug discovery are also discussed thoroughly. The book aims to address general questions and concerns about steroids, providing readers a useful resource on the subject.

Key Features:

- Provides comprehensive coverage on all aspects of steroids including steroid chemistry, biochemistry, medicinal potential, drug discovery and advances in target-binding interactions of steroid-based drugs

- Includes chapters dedicated to anabolic steroids and their abuse

- Designed as an accessible source of information for understanding steroidal drugs with structured chapters

- Includes references for advanced readers

Audience

General readers, learners in life sciences and medicine.

Preface

- Pp. i
Abid Hussain Banda*
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List of Contributors

- Pp. ii-iii (2)

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Terpenes, Terpenoids and Steroids: Properties, Biosynthesis and Functions

- Pp. 1-38 (38)
Masrat Maswal*, Meeshu Pandita, Shabnum Bashir

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An Overview of Natural Steroid Sources and their Therapeutic Profile

- Pp. 39-58 (20)
Mahalakshmi Krishnan, Livya Catherene Martin, Parimalanandhini Duraisamy, Sangeetha Ravi, Beulaja Manikandan, Janarthanan Sundaram, Ramar Manikandan*

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Synthesis of Steroids

- Pp. 59-83 (25)
Aneesa Muzaffar*, Umaiya Muzaffar, Rakesh Donepudi

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Biotransformation of Steroids: Accelerating Discovery of New Drugs in the Pharmaceutical Industry

- Pp. 84-97 (14)
Sadia Sultan*, Gurmeet Kaur Surindar Singh*, Kamran Ashraf, Muhammad Ashraf

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Biological Significance of Steroids

- Pp. 98-124 (27)
Sushma Devi*, Parveen Kumar, Gagandeep Kaur

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A Comprehensive Overview of Estrogen: Physiological and Pathological Insights

- Pp. 125-148 (24)
Rafia Jan*, Jahangir Nabi

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Plant Cardenolides: Multifunctional Medicinal Agents

- Pp. 149-174 (26)
Veenu Joshi, Akanksha Sahu, Ajay James, Amber Vyas, Neelu Joshi*

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Immunological Significance of Steroids and Implications for Immune Related Diseases

- Pp. 175-194 (20)
Sangeetha Ravi, Parimalanandhini Duraisamy, Mahalakshmi Krishnan, Livya Catherene Martin, Raman Thiagarajan, Angusamy Annapoorani, Munuswamy Arumugam, Sundaram Janarthanan, Ramar Manikandan*

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Heterocyclic Steroids

- Pp. 195-211 (17)
Mukesh M. Mudgal*, Mangesh M. Mudgal

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Spectroscopic Analysis of Steroids

- Pp. 212-285 (74)
Tabassum Siddiqui*, Asna Khan, Arfeen Iqbal

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Destructive Effects of Steroidal Drug Abuse and their Immunological Impact

- Pp. 286-308 (23)
Parimalanandhini Duraisamy, Sangeetha Ravi, Mahalakshmi Krishnan, Livya Catherene Martin, Beulaja Manikandan, Sundaram Janarthanan, Ramar Manikandan*

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Subject Index

- Pp. 309-314 (6)
Abid Hussain Banday*
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