Editor: Shazia Anjum

Advances in Organic Synthesis

Volume 18

eBook: US $59 Special Offer (PDF + Printed Copy): US $98
Printed Copy: US $69
Library License: US $236
ISSN: 1574-0870 (Print)
ISSN: 2212-408X (Online)
ISBN: 978-981-5040-80-7 (Print)
ISBN: 978-981-5040-79-1 (Online)
Year of Publication: 2023
DOI: 10.2174/97898150407911231801


Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.

Volume 18 presents 7 reviews focused on ionic materials, nanoparticles and nitrogen containing heterocycles in organic synthesis.

  • - Recent synthetic and biological advances in anti-cancer ferrocene-analogues and hybrids
  • - Synthesis of fused nitrogenated heterocycles: intramolecular povarov reaction
  • - Use of barbituric acid as a precursor for the synthesis of bioactive compound
  • - Ionic liquids as solvents and/or catalysts for organic synthesis
  • - Zinc oxide nanomaterials for biomedical applications
  • - Superhydrophobic polymeric nanocomposites coatings for effective corrosion protection
  • - Morphologies and properties of virgin and waste PP nanocomposites

Audience: Organic chemists, chemical engineers interested in chemical synthesis / synthetic techniques, polymer chemists


The series ‘Advances in Organic Synthesis’ are a dedicated set of different volumes covering all contemporary developments in organic synthesis. The contents of each volume are thoughtfully picked to capture the dire need of the readers and at the same time, it is rewarding to quench the thirst of researchers. The first chapter of volume 18 describes the latest syntheses and biological activities of anti-cancer Ferrocenes. Mehra and Lumb gave a brief account of the stable aromatic nature of ferrocene and bioferrocene compounds that possess reversible redox properties, and low toxicity that has also revolutionized the area of medicinal organometallic chemistry.

Masdeu et al. compiled a review on the synthesis of fused nitrogenated heterocycles using intramolecular Povarov Reaction. This strategy helped in synthesizing tri-, tetra-, penta-, hexa-, hepta-and octacyclic-fused heterocyclic compounds of diverse biological activities. While Singh and Kumari in their chapter 03 described the recent applications of barbituric acid as a synthetic precursor for the synthesis of various bioactive compounds. Barbituric acid can be employed in the condensation reaction as well as 5-/6- membered oxygen/nitrogen-containing heterocycles.

The use of ionic liquids (ILs) in organic syntheses has made a renaissance. It has revolutionized the entire trajectory of the synthetic pathway. In Chapter 4, Khokhar et al. described emerging applications of ILs as green solvents, green catalysts, and in coupling reactions. It depicts their remarkable use in environmentally benign organic synthesis which is the main focus of discussion in this chapter.

The last three chapters of these volumes are exclusively dedicated to the newly emerging field of nanotechnology. For example, chapter 05 of this volume illustrates the advanced use of Zinc oxide (ZnO) nanomaterials for biomedical applications. In this chapter, Bhuiyan et al. showed that ZnO nanomaterials could be developed by the organic synthesis process for excellent biocompatibility, selectivity, sensitivity, good chemical stability, non-toxicity, and fast electron transfer properties in a cost-effective manner. While Higazy et al., in their chapter 06 covered the contemporary development of nanocomposite hydrophobic coatings for effective corrosion protection. Organic-inorganic nanocomposites can be employed as outstanding anti-corrosive coatings to provide longevity of steel construction service. Overall, they gave an overview of present and advanced research developments, such as graphene nanocomposite surfaces, etc. Interestingly, the last chapter of this volume by Zdiri et al. covers the morphologies and properties of virgin and waste polypropylene nanocomposites. The article gives information on different types of nanoparticles used for the enhancement of thermo-mechanical and physical behaviors of PP nanocomposites. Moreover, it also discusses the improvements in the properties of waste PP by nanoparticles’ incorporation and the influence of clay nanoparticles on waste PP-based nanocomposites.

I hope that the readers will enjoy reading this volume which covers contemporary developments in organic syntheses. I would like to express my sincere thanks to the editorial staff of Bentham Science Publishers, particularly Ms. Asma Ahmed and Mr. Mahmood Alam for their constant help and support.

Shazia Anjum
Institute of Chemistry
The Islamia University of Bahawalpur