Editor: Rajesh Kumar Singh

Key Heterocyclic Cores for Smart Anticancer Drug–Design Part II

eBook: US $69 Special Offer (PDF + Printed Copy): US $119
Printed Copy: US $84
Library License: US $276
ISBN: 978-981-5040-05-0 (Print)
ISBN: 978-981-5040-04-3 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150400431220201

Introduction

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design.

Part II of the book set covers these topics:

  • - Anticancer targets for heterocyclic lead compounds
  • - Coumarin hybrids for cancer treatments
  • - Progress in nitrogen and sulphur-based heterocyclic compounds for their anticancer activity
  • - Imidazole as an anticancer heterocyclic ring
  • - Morpholine for profiling anticancer lead compounds
  • - Natural products as anticancer agents

Foreword

- Pp. i
Roman Lesyk
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Preface

- Pp. ii-iii (2)
Rajesh Kumar Singh
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List of Contributors

- Pp. iv

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Understanding Promising Anticancer Targets for Heterocyclic Leads: An Introduction

- Pp. 1-34 (34)
Shweta Sharma, Mymoona Akhter, Rajesh Kumar Singh*

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Impact of Coumarin Hybrids upon Imperative Clinical Targets against Cancer

- Pp. 35-78 (44)
Rohit Bhatia, Amandeep Singh, Bhupinder Kumar, Ravindra K. Rawal*

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Progress in Nitrogen and Sulphur-based Heterocyclic Compounds for their Anticancer Activity

- Pp. 79-104 (26)
Preeti Koli, Rajesh K. Singh*

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Imidazole Showing its Therapeutic Voyage as Anticancer Heterocyclic Ring

- Pp. 105-136 (32)
Ashwani K. Dhingra*, Bhawna Chopra, Akram Sidhu, Kumar Guarve, Ashish Gupta

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Morpholine: Pharmacophore Modulating Pharmacokinetic Properties of Anticancer Leads

- Pp. 137-173 (37)
Archana Kumari, Rajesh K. Singh*

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Natural Products as Anticancer Agents: Recent Advancement and Future Directions

- Pp. 174-207 (34)
Anurag Chaudhary, Kalpana Singh, Nishant Verma, Alok Sharma*

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Subject Index

- Pp. 208-218 (11)
Rajesh Kumar Singh
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