Editors: Somchai Chutipongtanate, Suradej Hongeng

Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine

eBook: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $118
Library License: US $356
ISBN: 978-981-5036-76-2 (Print)
ISBN: 978-981-5036-75-6 (Online)
Year of Publication: 2021
DOI: 10.2174/97898150367561210101

Introduction

Precision medicine is a disruptive innovation with a fast-evolving pace in the healthcare ecosystem. Precision medicine enables precise diagnosis and targeted treatment by considering individual variability in the abnormalities of causative genes and molecular drivers behind biochemical mechanisms. A vast amount of data created by advanced omics technologies is a foundation of precision medicine’s success, and the implications of the findings from these technologies can potentially improve clinical outcomes.

Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine presents essential information of molecular and translational research in precision medicine, with a specific focus on pediatrics. This book provides an accessible introduction to omics technologies, gives a detailed explanation of bioinformatics workflows to interpret high-throughput omics profiles for molecular diagnosis, and collects some of the cutting-edge research for precise therapeutics. Contributions to the book have been provided by experts in biomedical engineering and clinical practice, thus, bringing an informed perspective to the reader on each topic. The book is a valuable resource for postgraduate students, researchers, data scientists and clinicians interested in precision medicine, as well as researchers in the field of genetics and pediatrics who are interested in understanding the role of precision medicine in clinical practice.

Audience: Postgraduate researchers and professionals in the field of precision medicine and pediatrics; Data scientists working in medical informatics.

Contributors

Editor(s):
Somchai Chutipongtanate
Department of Pediatrics
Faculty of Medicine Ramathibodi Hospital
Mahidol University
Bangkok
Thailand


Suradej Hongeng
Department of Pediatrics
Faculty of Medicine Ramathibodi Hospital
Mahidol University
Bangkok
Thailand




Contributor(s):
Alexander Thorman
Department of Environmental and Public Health Sciences
University of Cincinnati
Cincinnati, OH
USA


Behrouz Shamsaei
Department of Environmental and Public Health Sciences
University of Cincinnati
Cincinnati, OH
USA
/
Department of Cancer Biology
University of Cincinnati College of Medicine
Cincinnati, Ohio
USA


Danai Khemasuwan
Division of Pulmonary and Critical Care Medicine
Virginia Commonwealth University
Richmond, VA
USA


Duangrurdee Wattanasirichaigoon
Division of Medical Genetics, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital
Mahidol University
Bangkok 10400
Thailand


Jarek Meller
Department of Biomedical Informatics
University of Cincinnati College of Medicine
Cincinnati, OH
USA
/
Division of Biomedical Informatics
Cincinnati Children’s Hospital Medical Center
USA
/
Department of Environmental and Public Health Sciences
University of Cincinnati
Cincinnati, OH
USA
/
Department of Informatics, Faculty of Physics, Astronomy and Informatics
Nicolaus Copernicus University
Toruń
Poland
/
Department of Electrical Engineering & Computer Science
University of Cincinnati
Cincinnati, OH
USA


James Reigle
Department of Biomedical Informatics
University of Cincinnati College of Medicine
Cincinnati
OH, USA


Kanit Bhukhai
Department of Physiology, Faculty of Science
Mahidol University
Bangkok
Thailand


Khyati Mehta
Division of Pathology and Laboratory Medicine
Cincinnati Children's Hospital Medical Center
Cincinnati, OH 45229
USA


Pankaj Dwivedi
Department of Cancer Biology
University of Cincinnati College of Medicine
Cincinnati, OH
USA


Parith Wongkittichote
Division of Medical Genetics
Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Bangkok 10400
Thailand
/
Department of Pediatrics
St. Louis Children's Hospital, Washington University School of Medicine, 1 Brookings Drive
St. Louis, MO 63130
USA


Patcharee Sriswasdi
Department of Anesthesiology Faculty of Medicine, Siriraj Hospital
Mahidol University
Bangkok
Thailand
/
Department of Anesthesiology, Critical Care & Pain Medicine
Boston Children's Hospital
Boston
USA


Phillip J. Dexheimer
Department of Biomedical Informatics
University of Cincinnati College of Medicine
Cincinnati, OH
USA


Pisut Pongchaikul
Chakri Naruebodindra Medical Institute (CNMI)
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Samut Prakan 10540
Thailand
/
Institute of Integrative Biology
University of Liverpool
Crown Street, Liverpool, L69 7ZB
UK


Sirirat Rattana-arpa
Department of Anesthesiology Faculty of Medicine, Siriraj Hospital
Mahidol University
Bangkok
Thailand
/
Department of Anesthesiology, Critical Care & Pain Medicine
Boston Children's Hospital
Boston
USA


Somchai Chutipongtanate
Department of Cancer Biology
University of Cincinnati College of Medicine
Cincinnati, OH
USA
/
Pediatric Translational Research Unit, Department of Pediatrics
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Bangkok
Thailand
/
Department of Clinical Epidemiology and Biostatistics
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Bangkok
Thailand
/
Chakri Naruebodindra Medical Institute
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Samut Prakan 10540
Thailand


Suparerk Bowornpinyo
Department of Biotechnology, Faculty of Science
Mahidol University
Bangkok
Thailand


Suradej Hongeng
Division of Hematology and Oncology, Department of Pediatrics
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Bangkok
Thailand


Thitinee Vanichapol
Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital
Mahidol University
Ratchathewi, Bangkok
Thailand
/
School of Biological Sciences, Faculty of Science
The University of Auckland
Auckland
New Zealand


Usanarat Anurathapan
Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital
Mahidol University
Ratchathewi, Bangkok
Thailand


Wararat Chiangjong
Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital
Mahidol University
Bangkook
Thailand