Chapter 7

Combinatorial Chemistry

Marcus Vinícius Nora de Souza

Abstract

Combinatorial chemistry is a methodology developed based on the synthesis of many compounds (hundreds, thousands, or even millions) in a simple chemical process building libraries of these compounds. In medicinal chemistry, an essential factor is the number of different molecules to be produced. For obtaining a leading compound and later a candidate drug, the biological evaluation of thousands of compounds is necessary. Therefore, the exercises below are based on combinatorial chemistry.

Total Pages: 165-175 (11)

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