Editors: Han-Sheng Chuang, Yi-Ping Ho

Series Title: Frontiers in Nanobiotechnology

Advances in Biosensing Technology for Medical Diagnosis

Volume 1

eBook: US $99 Special Offer (PDF + Printed Copy): US $156
Printed Copy: US $107
Library License: US $396
ISBN: 978-981-14-6476-8 (Print)
ISBN: 978-981-14-6480-5 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114648051200101


Biosensing technology is rapidly flourishing in recent years due to the advancement of bio-MEMS/NEMS. However, the booming development of biosensors has not been very well addressed to the unmet clinical needs. Advances in Biosensing Technology for Medical Diagnosis initiates a headway into the realm of cutting-edge diagnostic tools which are expected to become routine clinical practice. This book aims to broaden the readers’ horizon and guide them in tailoring different biosensing techniques for specific diagnostic procedures.

Key Features:

  1. -12 chapters cover several aspects of biosensing technologies including working principles and clinical validations
  2. -highlights the state-of-the-art biosensing technology developed in all fields
  3. -provides information about specific applications of novel biosensors used in clinical diagnosis
  4. -provides step-by-step guidance of microfabrication for biosensors
  5. -focuses on bridging the gap between the scientific and the clinical communities
  6. -provides information about the diagnostic applications of biosensors for different diseases (including infectious diseases and neurodegenerative diseases).
  7. -covers Information about unconventional nano/microfluidic biosensor systems
  8. -features contributions from renowned experts in the field of biomedical engineering

Advances in Biosensing Technology for Medical Diagnosis serves as a reference for healthcare providers and biomedical engineers who are interesting in biosensing techniques in medicine. The information provided in this reference will also benefit healthcare policymakers who are interested in new technologies that can impact the delivery of diagnostic services in healthcare systems.


Medical diagnosis is set to discover the cause of a person’s symptoms and to find the right treatment. An accurate medical diagnosis made in a timely manner is, therefore, the key to effective medical interventions and the subsequent survivorship. The existing clinical measures, usually involving invasive procedures, expensive and tedious operations, long turnaround time, or sometimes labor-intensive steps, may delay the clinical decisions. Biosensing technology is flourishing rapidly in recent years because of the advancement of micro/nano-fabrications. Despite the booming in all sorts of modern biosensors, most clinicians still prefer conventional medical instruments in diagnosis or making their therapeutic decisions. The barriers preventing the clinical communities from embracing new diagnostic technologies may be attributed to different levels of issues, including reproducible clinical validation, regulatory hurdles, compensations for the coverage of a new diagnostic procedure, and ethical concerns. To disseminate the cutting-edge diagnostic tools into routine clinical practice, the research and healthcare communities shall join the efforts to maximize the potential of recent biosensing advances. As a headway to broaden the readers’ horizon and to guide the readers in tailoring up-to-date biosensing techniques for specific embodiments, this book is aimed to bridge the gap between the scientific and clinical communities by providing valuable insights on the working principle of advanced biosensing technologies, and the scientific/clinical validations in establishing the analytical measures, especially, in medical applications. The inclusion of adequate background on the advancement in biosensing is expected to clear the hesitations of healthcare providers for adopting new diagnostic methods, encouraging the policy makers to reshape the regulations and compensations for diagnostic research and development, educating the next generation scientists to continue the efforts, as well as exposing the general audience to the latest development in relevant fields.

To this end, this book is organized in three parts, including part I: fundamentals of biosensors, part II: state-of-the-art biosensing technology, and part III: clinical practice with medical diagnostics. The opening chapter in part I describes the essentials of biosensors in medical diagnosis and how to evaluate the performance of a biosensor. In chapter 2, the micro-/nano-scale fabrication techniques are introduced to lay the foundation for subsequent realizations of biosensors in the following chapters. In part II, biosensors that cover five representative technological domains, including electrochemistry, electrical engineering, biochemistry, optical engineering, and fluid mechanics, are respectively discussed in chapters 3 through 7. In the last part, biosensors applied for different clinical purposes are specifically discussed in chapters 8 through 12 to highlight the potential use of biosensors in the clinical setting in the foreseeable future.

The editors are sincerely grateful to all the authors for their efforts in preparing the excellent and up-to-date chapters contained in the book. On behalf of these world-renowned experts in the field, the editors expect that this book will give the readers: (a) the state-of-the-art biosensing technologies developed in broad fields, (b) specific examples of novel biosensors used in medical diagnosis, and (c) step-by-step guidance of micro- and nano-fabrications in current biosensors. We hope readers who are interested in learning advances in biosensing technology may find this book not only containing plenty of scientific merits in this emerging field but also as informative as a tool book in their daily life.

Han-Sheng Chuang
National Cheng Kung University, Tainan, Taiwan
Yi-Ping Ho
Chinese University of Hong Kong, Shatin, Hong Kong


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