Editors: Atta-ur-Rahman , Zareen Amtul

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

Volume 7

eBook: US $69 Special Offer (PDF + Printed Copy): US $117
Printed Copy: US $83
Library License: US $276
ISSN: 2451-8883 (Print)
ISSN: 2214-7527 (Online)
ISBN: 978-981-14-4750-1 (Print)
ISBN: 978-981-14-4752-5 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114475251200701

Introduction

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.

The seventh volume of this series features reviews that cover the following topics related to the treatment of neurodegenerative diseases, epilepsy and stroke:

  1. -Fatty Acid Amides as a New Potential Therapeutic Agent in Multiple Sclerosis
  2. -Epileptic Seizures Detection Based on Non-Linear Characteristics Coupled with Machine Learning Techniques
  3. -Hampering Essential Tremor Neurodegeneration in Essential Tremor: Present and Future Directions
  4. -The Potential Therapeutic Role of the Melatoninergic System in Treatment of Epilepsy and Comorbid Depression
  5. -Modeling Neurodegenerative Diseases Using Transgenic Model of Drosophila
  6. -Genetic Basis in Stroke Treatment: Targets of Potent Inhibitors

Preface

The Central Nervous System is undeniably one of the most complex systems of the body. Neuroscientists all over the world are busy exploring this fascinating mystery of the biological system. There has been a tremendous increase in our knowledge about the brain, spinal cord, and peripheral system during the last couple of decades. Yet we still learn something new every day about the multifold obscurities of the nervous system.

The present book is an effort to inform our readers with the new milestones being explored and uncovered every day in the field of neuroscience. The six chapters cover state of the art cutting-edge contributions from eminent leaders in the field. Chapter 1 covers the role of fatty acid amides as new potential therapeutic agents to treat multiple sclerosis; chapter 2 highlights the use of machine learning techniques to detect epileptic seizures; chapter 3 outlines the present and future directions about the essential tremor neurodegeneration in essential tremor; chapter 4 presents the potential therapeutic role of the melatoninergic system to treat epilepsy and comorbid depression; chapter 5 evaluates how the transgenic model of drosophila is being used to model neurodegenerative diseases, and chapter 6 summarizes the importance of genetic basis in stroke as the potential drug target. In brief, each chapter covers a wide-ranging, analytically evaluated body of work such as pathogenesis, therapeutic evidence, targets, and mechanisms of action of therapeutics to treat brain disorders in a very compelling way.

I believe that this book will be of considerable interest for both experienced scientists from the neuroscience community as well as for beginners in the field.

I am grateful for the timely efforts made by the editorial personnel, especially Mr. Mahmood Alam (Director Publications), and Mrs. Salma Sarfaraz (Senior Manager Publications) at Bentham Science Publishers.



Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

&

Zareen Amtul
The University of Windsor
Department of Chemistry and Biochemistry
Windsor, ON
Canada

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.Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches.
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.Animal Models for Neurological Disorders.