Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research – Anti Allergy Agents

Volume 4

eBook: US $79 Special Offer (PDF + Printed Copy): US $134
Printed Copy: US $95
Library License: US $316
ISSN: 2452-3194 (Print)
ISSN: 2214-6938 (Online)
ISBN: 978-981-14-2838-8 (Print)
ISBN: 978-981-14-2839-5 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114283951200401


Frontiers in Clinical Drug Research - Anti-Allergy Agents is a book series comprising of a selection of updated review articles relevant to the recent development of pharmacological agents used for the treatment of allergies. The scope of the reviews includes clinical trials of anti-inflammatory and anti-allergic drugs, drug delivery strategies used to treat specific allergies (such as inflammation, asthma and dermatological allergies), lifestyle dependent modes of therapies and the immunological or metabolic mechanisms that are of interest to researchers as targets for new drugs.

The fourth volume of this series brings 5 reviews which cover the following topics:

- Anti-inflammatory and Immunomodulatory properties of medicinal plant products

- Helminth therapy: a new tool for treatment of allergic diseases

- An overview of anti-allergic medications in paediatric population

- In-silico approaches in drug discovery and design of anti-allergic agents

- Microbiota and allergy: possible Interventions

Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field.


Frontiers in Clinical Drug Research - Anti Allergy Agents comprises five comprehensive chapters on various treatment strategies for allergic conditions. In chapter 1, Bouyahya and Bakri focus on the anti-inflammatory and immunomodulatory properties of medicinal plant products. Research on these plants has allowed the discovery of bioactive molecules that have found a major role in the treatment of several diseases. In the second chapter, Dalia S. Ashour discusses helminth therapy (HT) as a new tool for the treatment of allergic diseases. This chapter also highlights the interaction between helminth infections and allergic diseases, the current status of HT, its challenges, and future prospects.

Dias and Dias present an overview of anti-allergic medications in the pediatric population in the next chapter of the book. Allergies in children are due to the interaction between environmental and genetic factors with the immune system. With the discovery of gene involvement and pathogenesis in allergic responses, the introduction of novel medications inhibiting allergic tissue responses should lead to improved treatments.

Roy et al., in chapter 4 discuss researches on different targets for anti-allergic agents. They present a brief overview on in silico methods as well as computational studies carried out on the targets. This can be helpful in accelerating the drug discovery for novel and more potent anti- allergic agents that can be useful for controlling diseases such as bronchial asthma, allergic rhinoconjunctivitis and atopic dermatitis.

In the last chapter Banerjee et al discuss the role of the microbiota in the immune system and its subsequent effects on allergic reactions. They also discuss the various possible interventions, including the use of probiotics, prebiotics, and synbiotics as potential anti-allergic agents.

I hope that this volume will be of great interest to the scientific community and it will contribute to the development of more effective therapeutic agents to combat various allergies and pulmonary ailments.

I would like to thank all the authors for their excellent contributions. I am also grateful to the excellent team of Bentham Science Publishers, particularly Mr. Mahmood Alam (Director Publications), Mr. Obaid Sadiq (Incharge Books Department), and Ms. Asma Ahmed (Senior Manager Publications) for their support and hard work.

Prof. Atta-ur-Rahman, FRS
Honorary Life Fellow,
Kings College,
University of Cambridge,


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