Editors: Atta-ur-Rahman, FRS , Prof. Muhammad Iqbal Choudhary

Frontiers in Cardiovascular Drug Discovery

Volume 5

eBook: US $79 Special Offer (PDF + Printed Copy): US $134
Printed Copy: US $95
Library License: US $316
ISSN: 2452-3267 (Print)
ISSN: 1879-6648 (Online)
ISBN: 978-981-14-1323-0 (Print)
ISBN: 978-981-14-1324-7 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114132471200501

Introduction

Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology.

The fifth volume of the series covers the following topics:

- The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors

- The Role of SGLT2i in the Prevention and Treatment of Heart Failure

- Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019)

- Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases?

- Treatment of Raynaud’s Phenomenon

- Traditional Medicine Based Cardiovascular Therapeutics

- Cardiovascular Disease: A Systems Biology Approach

Preface

- Pp. i-ii (2)
Atta-ur-Rahman and M. Iqbal Choudhary
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List of Contributors

- Pp. iii-iv (2)
Atta-ur-Rahman and M. Iqbal Choudhary
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The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors

- Pp. 1-35 (35)
Sudarshan Ramachandran, Mithun Bhartia and Carola S. König

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The Role of SGLT2i in the Prevention and Treatment of Heart Failure

- Pp. 36-64 (29)
Hasan AlTurki, Ahmed AlTurki, Mark Sherman, Abhinav Sharma and Thao Huynh

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Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019)

- Pp. 65-107 (43)
Angelo Piato and Cedric Stephan Graebin

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Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases?

- Pp. 108-163 (56)
Leidyanne Ferreira Gonçalves, Thereza Cristina Lonzetti Bargut and Caroline Fernandes-Santos

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Treatment of Raynaud’s Phenomenon

- Pp. 164-210 (47)
Sevdalina Nikolova Lambova

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Traditional Medicine Based Cardiovascular Therapeutics

- Pp. 211-233 (23)
Sriram Kumar, Rekha Ravindran, Sakthi Abbirami Gowthaman, Sujata Roy and Johanna Rajkumar

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Cardiovascular Disease: A Systems Biology Approach

- Pp. 234-250 (17)
Sujata Roy and Ashasmita S Mishra

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Subject Index

- Pp. 251-263 (13)
Atta-ur-Rahman and M. Iqbal Choudhary
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