Editors: Atta-ur-Rahman , Muhammad Iqbal Choudhary

Frontiers in Anti-infective Drug Discovery

Volume 9

eBook: US $89 Special Offer (PDF + Printed Copy): US $151
Printed Copy: US $107
Library License: US $356
ISBN: 978-1-68108-830-3 (Print)
ISBN: 978-1-68108-829-7 (Online)
Year of Publication: 2021
DOI: 10.2174/97816810882971210901


This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.

Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively.

- Use of preclinical and early clinical data for accelerating antimicrobial drug development

- Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs

- Scope and limitations on the potent antimicrobial activities of hydrazone derivatives

- Current scenario of anti-leishmanial drugs and treatment

- Dengue hemorrhagic fever: the potential repurposing drugs


- Pp. i
Atta-ur-Rahman, M. Iqbal Choudhary
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List of Contributors

- Pp. ii
Atta-ur-Rahman, M. Iqbal Chaudhary
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Use of Preclinical and Early Clinical Data for Accelerating Antimicrobial Drug Development

- Pp. 1-24 (24)
Mahesh N. Samtani*, Amarnath Sharma, Partha Nandy
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Post-Translational Modifications: Host Defence Mechanism, Pathogenic Weapon, and Emerged Target of Anti-Infective Drugs

- Pp. 25-122 (98)
Maria Amprazi, Anastasia Tomatsidou, Dimitra Paliogianni, Vasiliki E. Fadouloglou*
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Scope and Limitations on the Potent Antimicrobial Activities of Hydrazone Derivatives

- Pp. 123-155 (33)
Jean Michel Brunel*
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Current Scenario of Anti-Leishmanial Drugs and Treatment

- Pp. 156-186 (31)
Priyanka H. Mazire, Amit Roy*
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Dengue Hemorrhagic Fever: The Potential Repurposing Drugs

- Pp. 187-207 (21)
Wattana Leowattana*, Pathomthep Leowattana, Tawithep Leowattana
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Subject Index

- Pp. 208-217 (10)
Atta-ur-Rahman, M. Iqbal Chaudhary
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.Biotechnology and Drug Development for Targeting Human Diseases.
.Enzymatic Targets for Drug Discovery Against Alzheimer
.Applied Computer-Aided Drug  Design: Models and Methods.
.Medicinal Plants, Phytomedicines and Traditional Herbal Remedies for Drug Discovery and Development against COVID-19.