Editor: Hemant Khanna

Molecular Bases of Neurodegenerative Disorders of the Retina

eBook: US $39 Special Offer (PDF + Printed Copy): US $108
Printed Copy: US $89
Library License: US $156
ISBN: 978-1-68108-549-4 (Print)
ISBN: 978-1-68108-548-7 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810854871170101


This book focuses on the physiology and molecular biology of the front and back regions of the eye. Specifically, the chapters of this book cover topics that explain currently less understood aspects of retinal health as well as the use of zebrafish models to understand the molecular pathogenesis of associated diseases. This includes retinitis pigmentosa, diabetic retinopathy ciliopathies in the eye, rhodopsin trafficking and associated disorders, and the biochemistry of cone defects. This book serves as a useful reference for scientists and graduate students seeking to understand protein trafficking mechanisms and metabolic control in retinal diseases.

Indexed in: BIOSIS Previews, Book Citation Index.


- Pp. i
Hemant Khanna
Download Free

List of Contributors

- Pp. ii
Hemant Khanna
Download Free

Ciliary Trafficking in Vertebrate Photoreceptors

- Pp. 1-15 (15)
Hemant Khanna
View Abstract

Zebrafish Models of Photoreceptor Ciliopathies

- Pp. 16-38 (23)
Brian D. Perkins
View Abstract

Inositol Phosphatases in Retinal Ciliary Disorder

- Pp. 39-53 (15)
Cathleen Wallmuth, Na Luo, Yang Sun
View Abstract

Understanding the Pathogenesis of Neurodegeneration in Diabetic Retinopathy (DR)

- Pp. 54-73 (20)
Shahna Shahulhameed, Subhabrata Chakrabarti, Jay K. Chhablani, Inderjeet Kaur
View Abstract

Rhodopsin Traffics to the Rod Outer Segment in the Absence of Homodimeric and Heterotrimeric Kinesin-2

- Pp. 74-85 (12)
Li Jiang, Jeanne M. Frederick, Wolfgang Baehr
View Abstract

The Molecular Links between Mutations in RDS and Diseases of the Retina

- Pp. 86-100 (15)
Michael W. Stuck, Shannon M. Conley, Muna I. Naash
View Abstract

Rhodopsin-Regulated Grb14 Trafficking to Rod Outer Segments: Functional Role of Grb14 in Photoreceptors

- Pp. 101-108 (8)
Raju V.S. Rajala
View Abstract

Cellular Mechanisms of Cone Defects in Cyclic Nucleotide-Gated Channel Deficiency

- Pp. 109-124 (16)
Xi-Qin Ding, Hongwei Ma, Martin Biel, Stylianos Michalakis
View Abstract

Subject Index

- Pp. 125-132 (8)
Hemant Khanna
Download Free


.Optical Coherence Tomography Angiography for Choroidal and Vitreoretinal Disorders – Part 1.
.Optical Coherence Tomography Angiography for Choroidal and Vitreoretinal Disorders – Part 2.
.Diabetes and the Eye: Latest Concepts and Practices.
.Contemporary Scleral Lenses: Theory and Application.