Preface

The book series Frontiers in Clinical Drug Research-HIV presents important recent developments in the form of cutting edge reviews written by eminent authorities in the field. The chapters in this 4^th volume are mainly focused on different types of HIV-1 inhibitors (integrase inhibitors, protease inhibitors, entry inhibitors, etc.), magnetic nanotherapeutics, and sexually transmitted co-infections.

Alluri and Ganguly in Chapter 1 discuss the design and synthesis of HIV-1 protease inhibitors based on a cyclic sulfonamide core structure. Sagar et al., in chapter 2 discuss the importance of magnetic nanocarriers for delivering therapeutics which can exert changes at genetic levels. Chapter 3 by Watts et al., describes the synthesis of currently FDA approved integrase inhibitor drugs and other HIV drugs developed through flow technology.

Chapter 4 by Yi-Qun Kuang focuses on the development and clinical progress on chemokine receptor-based HIV entry inhibitors. Cobucci et al., in chapter 5, discuss the most prevalent co-infections found in HIV carriers and their epidemiology, clinical features and evidence-based treatments.

I am grateful to all the eminent scientists for their excellent contributions. I also express my gratitude to the editorial staff, particularly Mr. Mahmood Alam (Director Publication), Mr. Shehzad Naqvi (Editorial Manager Publications) and Ms. Fariya Zulfiqar (Manager Publications) for their hard work and persistent efforts.