Frontiers in Clinical Drug Research- HIV

Volume 4

by

Atta-ur-Rahman, FRS

DOI: 10.2174/97816810852651170401
eISBN: 978-1-68108-526-5, 2018
ISBN: 978-1-68108-527-2
ISSN: 2468-0397 (Print)
ISSN: 2352-5916 (Online)



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Indexed in: Scopus.

Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learn...[view complete introduction]
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Table of Contents

Preface

- Pp. i
Atta-ur-Rahman
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List of Contributors

- Pp. ii
Atta-ur-Rahman
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Design and Synthesis of HIV-1 Protease Inhibitors

- Pp. 1-33 (33)
Sesha S. Alluri and Ashit K. Ganguly

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Potential Magnetic Nanotherapeutics for Management of neuroAIDS

- Pp. 34-60 (27)
Vidya Sagar, Arti Vashist and Madhavan Nair

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Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing

- Pp. 61-104 (44)
Omobolanle Janet Jesumoroti, Faith Akwi and Paul Watts

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The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors

- Pp. 105-137 (33)
Yi-Qun Kuang

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Sexually Transmitted Co-infections in Persons Living with HIV

- Pp. 138-152 (15)
Ana Paula Ferreira Costa, Marcos Gonzaga dos Santos and Ricardo Ney Oliveira Cobucci

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Subject Index

- Pp. 153-157 (5)
Atta-ur-Rahman
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Preface

The book series Frontiers in Clinical Drug Research-HIV presents important recent developments in the form of cutting edge reviews written by eminent authorities in the field. The chapters in this 4th volume are mainly focused on different types of HIV-1 inhibitors (integrase inhibitors, protease inhibitors, entry inhibitors, etc.), magnetic nanotherapeutics, and sexually transmitted co-infections.

Alluri and Ganguly in Chapter 1 discuss the design and synthesis of HIV-1 protease inhibitors based on a cyclic sulfonamide core structure. Sagar et al., in chapter 2 discuss the importance of magnetic nanocarriers for delivering therapeutics which can exert changes at genetic levels. Chapter 3 by Watts et al., describes the synthesis of currently FDA approved integrase inhibitor drugs and other HIV drugs developed through flow technology.

Chapter 4 by Yi-Qun Kuang focuses on the development and clinical progress on chemokine receptor-based HIV entry inhibitors. Cobucci et al., in chapter 5, discuss the most prevalent co-infections found in HIV carriers and their epidemiology, clinical features and evidence-based treatments.

I am grateful to all the eminent scientists for their excellent contributions. I also express my gratitude to the editorial staff, particularly Mr. Mahmood Alam (Director Publication), Mr. Shehzad Naqvi (Editorial Manager Publications) and Ms. Fariya Zulfiqar (Manager Publications) for their hard work and persistent efforts.


Prof. Atta-ur-Rahman, FRS
Kings College
University of Cambridge
Cambridge
UK

List of Contributors

Editor(s):
Prof. Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK




Contributor(s):
Ana Paula Ferreira Costa
Avenida Salgado Filho
Natal, RN
Brazil


Arti Vashist
Center for Personalized Nanomedicine/Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine
Florida International University
Miami, FL - 33199
USA


Ashit K. Ganguly
Stevens Institute of Technology
1 Castle Point Terrace, Hoboken, NJ
USA


Faith Akwi
Nelson Mandela University
University Way
Port Elizabeth, 6031
South Africa


Madhavan Nair
Center for Personalized Nanomedicine/Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine
Florida International University
Miami, FL - 33199
USA


Marcos Gonzaga dos Santos
Avenida Salgado Filho
Natal, RN
Brazil


Omobolanle Janet Jesumoroti
Nelson Mandela University
University Way
Port Elizabeth, 6031
South Africa


Paul Watts
Nelson Mandela University
University Way
Port Elizabeth, 6031
South Africa


Ricardo Ney Oliveira Cobucci
Avenida Salgado Filho
Natal, RN
Brazil


Sesha S. Alluri
Stevens Institute of Technology
1 Castle Point Terrace, Hoboken, NJ
USA


Vidya Sagar
Center for Personalized Nanomedicine/Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine
Florida International University
Miami, FL - 33199
USA


Yi-Qun Kuang
Center for Translational Medicine, Huaihe Clinical College
Huaihe Hospital of Henan University
Kaifeng, Henan
China




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