Editors: Juan Antonio Vílchez, María Dolores Albaladejo-Otón

New Trends in Biomarkers and Diseases Research: An Overview

eBook: US $129 Special Offer (PDF + Printed Copy): US $247
Printed Copy: US $183
Library License: US $516
ISBN: 978-1-68108-496-1 (Print)
ISBN: 978-1-68108-495-4 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810849541170101

Introduction

Biomarkers are any measurable biochemical characteristics of an organism that reflect a particular physiological state. Biomarkers can take many different forms including particular proteins or peptides, antibodies, cell types, metabolites, hormones, enzyme levels, compounds related to genomics, etc. A biomarker can also be a substance introduced into a patient to assess the internal organ systems role.

In medicine, biomarkers considered as compounds isolated from serum, urine, or other fluids, can be used as an indicator of the presence or severity of a particular disease state., improving our knowledge of the pathophysiology of many diseases. The use of biomarkers is becoming a fundamental practice in medicine. Biomarker research involves a significantly greater scope of laboratory medicine.

This monograph presents information on several types of biomarkers for general pathologies. (preeclampsia, metabolic syndrome, iron metabolism, bone disease, liver function, renal function), cardiovascular pathology (including atrial fibrillation, peripheral artery disease, thrombotic disorders) and sepsis. Additional information on endocrine and salivary biomarkers is also presented.

New Trends in Biomarkers and Diseases Research: An Overview is an update of the present and future of clinical contribution and the correct interpretation of biomarkers. In addition to clinicians, this book is aimed to professionals of own laboratory medicine, university researchers and clinicians in general.

Foreword

- Pp. i
Jordi Ordoñez-Llanos
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Preface

- Pp. ii
Juan Antonio Vílchez
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List of Contributors

- Pp. iiii-v (3)
Juan Antonio Vílchez
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Biomarkers in Pre-eclampsia: Is it Possible to Predict it?

- Pp. 1-22 (22)
Ana Martínez-Ruiz, Irene De-Miguel-Elízaga and Natalia Sancho- Rodríguez

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Metabolic Syndrome and Inflammation: Interrelated Aspects and Biomarkers Involved

- Pp. 23-56 (34)
Jose Pedregosa-Díaz, María Henar García-Lagunar and María Dolores Albaladejo-Otón

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Liver Fibrosis Biomarkers

- Pp. 57-79 (23)
Iria Cebreiros-López

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Iron Metabolism: New Biomarkers Implicated

- Pp. 80-120 (41)
Ana Hernando- Holgado and M. Pilar Gallego-Hernanz

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Equations of Glomerular Filtration Rate and Biomarkers to Evaluate Renal Function: A Perspective

- Pp. 121-152 (32)
Irene Gutiérrez-García and Juan Antonio Vílchez

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Biomarkers of Bone Turnover: Molecular Approaches and Clinical Relevance

- Pp. 153-188 (36)
Irene de Miguel-Elízaga, Ana Martínez-Ruíz, Natalia Sancho-Rodríguez and Miriam Martínez-Villanueva

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Vitamin D: from Bone Metabolism to New Applications

- Pp. 189-222 (34)
Marta M. Castañeda San Cirilo

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New Research About Biomarkers and Atrial Fibrillation

- Pp. 223-250 (28)
Diana Hernández-Romero, Vanessa Roldán, Mariano Valdés and Francisco Marín

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Current Trends in Biomarkers of Acute Coronary Syndrome

- Pp. 251-284 (34)
Carmen María Puche-Morenilla, Luis García de Guadiana Romualdo and Juan Antonio Vílchez

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Physiopathology of Thrombotic Diseases and Platelet Derived Biomarkers

- Pp. 285-308 (24)
Silvia Montoro- García and Sara María Martínez-Sánchez

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Importance of Biomarkers in Heart Failure: Classic and New Aspects

- Pp. 309-340 (32)
Juan Antonio Vílchez, Pablo Perez-Cañadas, Francisco Marín and Jordi Ordóñez-Llanos

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Emerging Biomarkers in Peripheral Artery Disease

- Pp. 341-370 (30)

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Early Neonatal Sepsis Biomarkers

- Pp. 371-396 (26)
Natalia Sancho-Rodríguez, Marta Sancho-Rodríguez, Irene De-Migue-Elízaga and Ana Martínez-Ruiz

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Sepsis: Traditional and Emergent Biomarkers for Diagnosis and Prognosis

- Pp. 397-435 (39)
Luis García de Guadiana-Romualdo, Patricia Esteban-Torrella and María Dolores Albaladejo-Otón

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Biomarkers in Saliva as a Tool for Health Diagnosis

- Pp. 436-468 (33)
Ana M. Moreno-Fuentes and Carmen Nieto-Sánchez

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Endocrine Disruptors: What Do We Know about the Effects and Risk Factors in Humans?

- Pp. 469-504 (36)
Africa de Béjar-Almira, Alice Charlotte Viney and Marta M. Castañeda San Cirilo

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Monitoring of Monoclonal Antibodies, A New Window in the Use of Biomarkers in Pharmacology

- Pp. 505-527 (23)
Enrique Jiménez-Santos, Iris Muñoz-García, Maria S García-Simón, Jose Pedregosa-Díaz and Juan Antonio Vílchez

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Subject Index

- Pp. 528-541 (14)
Juan Antonio Vílchez
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