Editors: Atta-ur-Rahman, FRS , Prof. Muhammad Iqbal Choudhary

Frontiers in Cardiovascular Drug Discovery

Volume 4

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISSN: 2452-3267 (Print)
ISSN: 1879-6648 (Online)
ISBN: 978-1-68108-400-8 (Print)
ISBN: 978-1-68108-399-5 (Online)
Year of Publication: 2019
DOI: 10.2174/97816810839951180401


Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology.

The fourth volume of the series covers the following topics:

  • - Aspirin administration
  • - Adenosine receptor targeting for cardiovascular therapy
  • - Drug treatment of patients with coronary stenting
  • - Immunosuppressive drugs in heart transplantation
  • - PCSK9 inhibition for lowering LDL-C levels


- Pp. i
Atta-ur-Rahman, M. Iqbal Choudhary
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List of Contributors

- Pp. ii
Atta-ur-Rahman, M. Iqbal Choudhary
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Should the Argument About Aspirin Dosing be About Frequency Rather the Dose?

- Pp. 1-15 (15)
Nicholas B. Norgard, Priya Jain, Jonathon R. Enriquez
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Adenosine Receptors and Drug Discovery in the Cardiovascular System

- Pp. 16-64 (49)
Maan T. Khayat, Ahmad Hanif, Werner J. Geldenhuys, Mohammed A. Nayeem
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Platelet Reactivity in Patients with Coronary Stenting Treated with Dual Antiplatelet Therapy and after Withdrawal of Clopidogrel: Impact of Bioactive Titanium Stent versus Everolimus-coated Stent

- Pp. 65-82 (18)
Amparo Hernandiz, Jose Luis Díez, Antonio Moscardo, Ana Latorre, Maria Dolores Domenech, Maria Teresa Santos, Juana Valles
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Immunosuppressive Drugs in Heart Transplantation

- Pp. 83-147 (65)
Sule Apikoglu-Rabus, Murat B. Rabus, Rashida Muhammad Umar
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PCSK9 Inhibition with Evolocumab Reaching Physiologic LDL-C Levels for Reducing Atherosclerotic Burden and Cardiovascular Disease-The Full Landscape

- Pp. 148-185 (38)
Enrique C. Morales-Villegas, Kausik K. Ray
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Subject Index

- Pp. 186-194 (9)
Atta-ur-Rahman, M. Iqbal Choudhary
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