Editors: Atta-ur-Rahman, FRS , M. Iqbal Choudhary

Frontiers in Anti-Cancer Drug Discovery

Volume 8

eBook: US $39 Special Offer (PDF + Printed Copy): US $138
Printed Copy: US $119
Library License: US $156
ISSN: 2451-8395 (Print)
ISSN: 1879-6656 (Online)
ISBN: 978-1-68108-390-2 (Print)
ISBN: 978-1-68108-389-6 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810838961170801


Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The eighth volume of the series features chapters covering the following topics:

  • - T cells in gastrointestinal cancers
  • - The pharmacology of adjudin – a male contraceptive with anti-cancer properties
  • - Manipulating the tumor microenvironment
  • - Treatment of hepatocellular carcinoma
  • - Gold-based compounds as potential anti-cancer drug candidates
  • - Oral nanostructure drug delivery for anti-cancer treatment


- Pp. i-ii (2)
Atta-ur Rahman, M. Iqbal Choudhary
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List of Contributors

- Pp. iii-iv (2)
Atta-ur Rahman, M. Iqbal Choudhary
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T Cells in Gastrointestinal Cancers: Role and Therapeutic Strategies

- Pp. 1-28 (28)
Carolina V. De Almeida, Ramon Kaneno, Amedeo Amedei
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Adjudin - A Male Contraceptive with Anti-Cancer, Anti-Neuroinflammation and Anti-Ototoxicity Activities

- Pp. 29-45 (17)
Yan-ho Cheng, Weiliang Xia, Xiang Xiao, Elizabeth Tang, Haiqi Chen, Qing Wen, Ying Gao, Dolores Mruk, Bruno Silvestrini, C. Yan Cheng
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Manipulating the Tumor Microenvironment: Opportunities for Therapeutic Targeting

- Pp. 46-71 (26)
Peace Mabeta, Michael S. Pepper
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Current and Emerging Cancer Therapies for Treatment of Hepatocellular Carcinoma

- Pp. 72-103 (32)
Sarwat Fatima, Nikki P. Lee, Zhao Xiang Bian
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Recent Development (from 2013 to 2015) of Gold- Based Compounds as Potential Anti-Cancer Drug Candidates

- Pp. 104-122 (19)
Raymond Wai-Yin Sun, Chunxia Chen, Man-Kin Tse, Chih-Chiang Chen, Albert S.-C. Chan
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Oral Delivery by Nanostructures for the Treatment of Cancer

- Pp. 123-159 (37)
Mahendar Porika, Rama Narsimha Reddy Anreddy, Radhika Tippani, Srividya Lonkala
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Subject Index

- Pp. 160-168 (9)
Atta-ur Rahman, M. Iqbal Choudhary
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