Editor: José Juan Escobar-Chávez

Series Title: Current Technologies to Increase the Transdermal Delivery of Drugs

Physical Penetration Enhancers: Therapeutic Applications and Devices

Volume 2

eBook: US $129 Special Offer (PDF + Printed Copy): US $219
Printed Copy: US $155
Library License: US $516
ISSN: 2468-7375 (Print)
ISSN: 2468-7383 (Online)
ISBN: 978-1-68108-364-3 (Print)
ISBN: 978-1-68108-363-6 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810836361160201


This volume covers the methods of using skin penetrating agents, the therapeutic applications of physical penetration enhancers and devices in the market. Chapters cover topics such as transdermal drug delivery through iontophoresis, gene therapy, physiotherapy, skin disorders, vaccination, and pharmacology. Devices covered in this volume include micro needles, nano-carrier and gene delivery systems.

This volume is a handy resource for professionals in medicine (dermatologists), biopharmacy, pharmaceutical technology, drug design and development (scientists and pharmaceutical R&D executives).


Physical penetration enhancers: Therapeutic applications and devices”, is the second volume of the series “Current technologies to increase the transdermal delivery of drugs” from Bentham Science Publishers. This book provides an overview of main current physical enhancers in the therapeutical and pharmacy field. The importance of therapeutical applications of physical enhancers, and devices existing in the market will be addressed in each chapter. Exclusive chapters on Iontophoresis, Sonophoresis, Electroporation, Microneedles, Radiofrequency and more recently the use of nanoparticles in combination with the above mentioned physical enhancers, highlighting their main therapeutic applications will be included in this book.

Currently, there are no unique books available on therapeutical applications of physical penetration enhancers and currently devices in the market. Brief chapters and books describing only one of the physical enhancers or only one of the therapeutical applications (i.e., transdermal drug delivery) of these enhancers are available to readers in some drug delivery or toxicology books. For these reasons, more detailed information about therapeutical applications (drug delivery, gene therapy, physiotherapy, skin disorders, vaccination, etc.) is now needed. This book presents a general overview of the theoretical and therapeutic aspects of iontophoresis, electroporation, sonophoresis, microneedles, radiofrequency and nanocarriers systems in combination with physical enhancers. Such a generalized approach would be helpful in medicine, pharmacy, drug discovery, drug delivery and toxicological research.

A comprehensive book which provides the basis and updated therapeutical research information is necessary. For this fact, this e-book will be an interesting option that could be used by students and academics of medicine, biopharmacy, pharmaceutical technology, design and development of drugs, pharmacology, by physicians, dermatologists, scientists and pharmaceutical R & Ds. The book also will be useful for medicine, pharmacy, pharmacology and pharmaceutical technology departments of different Universities all over the world.

In summary, this e-book reviews the therapeutical uses of physical enhancers such as iontophoresis, sonophoresis, electroporation, microneedles, radiofrequency and nanocarriers in combination with physical enhancers. After an introduction, definition, mechanisms of action, the focus turns to the relevance of therapeutical applications studies and finally the different physical enhancer devices in the market.

Dr. José Juan Escobar-Chávez
Universidad Nacional Autónoma de México
Facultad de Estudios Superiores Cuautitlán
Unidad de Investigación Multidisciplinaria
Laboratorio 12: Sistemas transdérmicos y materiales nanoestructurados
Av. Cuautitlán-Teoloyucan. San Sebastián Xhala
Cuautitlán Izcalli, Estado de México. C.P 54714,


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