Editor: Constantin Apetrei

Series Title: Frontiers in Bioactive Compounds

Natural Sources, Physicochemical Characterization and Applications

Volume 1

eBook: US $129 Special Offer (PDF + Printed Copy): US $219
Printed Copy: US $155
Library License: US $516
ISSN: 2468-6395 (Print)
ISSN: 2468-6409 (Online)
ISBN: 978-1-68108-342-1 (Print)
ISBN: 978-1-68108-341-4 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810834141160101


This volume presents different aspects related to bioactive compounds, starting with their natural state in raw sources, physicochemical characterization and employment in pharmacy and medicine. The volume is divided into three parts. The first part describes the chemicals structure of bioactive compounds from different natural sources such as olive oils, wines, and medicinal plants. Special attention has been given to identifying the bioactive composition within variations of these natural sources (for example, extra virgin, ordinary or lampante olive oils). The second part of the volume presents the principal methods used for detecting, identifying and quantifying bioactive compounds. Emphasis is given to the use of different types of sensors or biosensors, and multisensor systems in combination with analytical techniques. The final part explains the principal methods for protection of bioactive compounds and the implication of bioactive compounds in pharmacy. This volume is a useful guide for novice researchers interested in learning research methods to study bioactive compounds.


This book presents the composition and health benefices of bioactive compounds from natural products, and the principal methods used for separation, detection, quantification and protection of bioactive compounds. A special attention is devoted to membrane model interactions as well as to sensors and biosensors development.

The book is organized in the following way:

Chapter 1 deals with the description of chemical composition of olive oil, highlighting the chemical structure and health benefices of biologic active compounds present in this food.

Chapter 2 describes the composition, chemical structures and benefices of bioactive compounds from red wine. A special attention is devoted to polyphenolic compounds, especially to resveratrol, a compound with multiple benefices and without toxic effects.

Chapter 3 presents the recent advances in the analysis of bioactive compounds based on molecular recognition. Separation techniques (solid phase extraction, chromatography, electrophoresis), and sensing (electrochemical, optical, etc.) are revised.

Chapter 4 describes the electrochemical sensors, especially voltammetric sensors, dedicated to the analysis of antioxidants. The principal methods used to improve voltammetric sensors selectivity and sensitivity by modifying the surface using chemical or biological materials are described, also.

Chapter 5 presents the most representative and novel biosensors for the detection of polyphenols, biogenic amines, mycotoxins and allergens in wine, emphasizing the wealth of biosensing strategies and the particularities of wine as a complex analytical matrix.

Chapter 6 provides a review of the most recent works in the field of electronic sensory system for characterization of bioactive compounds, from electronic noses to sensors and biosensors.

Chapter 7 describes the use of Langmuir monolayers as cell membrane models made to interact with bioactive compounds. Trends in the field are discussed as motivation for innovative research to bridge the gap between biology (and medicine) and the physicochemical framework used in cell membrane modeling.

The book closes with Chapter 8 presenting the newest information about the bioactive compounds encapsulation, which ensures the stability of the volatile compounds during thermal processing, the protection of bioactive components against environmental factors, the increase of the solubility of bioactive compounds, and the controlled release of bioactive components.

I appreciatively acknowledge the distinguished specialists who contributed in this book. I consider myself privileged to have had the occasion to work together with colleagues of universities from Spain, Italy, Brazil and Romania. Finally, I want to thank Bentham Science Publishers for the opportunity to edit this book.

Constantin APETREI
Department of Chemistry, Physics and Environment
Faculty of Sciences and Environment
“Dunarea de Jos” University of Galati
47 Domneasca Street
800008 Galati, Romania
Phone: +40-0236460328
Fax: +40-0236461353
E-mail: apetreic@ugal.ro


.The Chemistry Inside Spices & Herbs: Research and Development.
.Botanicals and Natural Bioactives: Prevention and Treatment of Diseases.
.Frontiers In Medicinal Chemistry.
.Alkaloids and Other Nitrogen-Containing Derivatives.