Polarity index in Proteins-A Bioinformatics Tool

by

Carlos Polanco

DOI: 10.2174/97816810826911160101
eISBN: 978-1-68108-269-1, 2016
ISBN: 978-1-68108-270-7



Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, EBSCO.

Polarity is a physico-chemical property that characterizes the electromagnetic stability of a protein and can be used to predict its p...[view complete introduction]
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Amyloid Proteins

- Pp. 59-70 (12)

Carlos Polanco

Abstract

This chapter describes the main results obtained when the polar profile of peptides associated to Amyloidosis is determined by polarity index method (Sect. 3.3), and the relation these peptides have with a group of proteins identified by their structure-function called natively folded proteins, partially folded proteins, and natively unfolded proteins. Amyloidosis is a term that groups a set of mental diseases with neurodegenerative characteristics, caused by the agglomeration of natively unfolded proteins on the neurons and lipoproteins. This chapter shows that the proteins that express neurons are natively folded proteins.

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