Editors: Atta-ur-Rahman , M. Iqbal Choudhary , Allen B. Reitz

Frontiers in Medicinal Chemistry

Volume 9

eBook: US $39 Special Offer (PDF + Printed Copy): US $138
Printed Copy: US $119
Library License: US $156
ISSN: 1567-2042 (Print)
ISSN: 1875-5763 (Online)
ISBN: 978-1-68108-250-9 (Print)
ISBN: 978-1-68108-249-3 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810824931160901

Introduction

“Frontiers in Medicinal Chemistry” is an E-book series devoted to reviews on research topics relevant to medicinal chemistry and allied disciplines. “Frontiers in Medicinal Chemistry” covers developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. This E-book series is essential for any medicinal chemist who wishes to be updated on the latest and the most important advances in the field.

“Frontiers in Medicinal Chemistry” covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. This eBook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.

This volume features reviews on the following topics:

• Purinergic receptors and pain

• Cytochrome c – cardiolipin interactions in cells

• Dipeptidyl peptidase-4 (CD26) functions and inhibition

• Peptides regulating angiogenesis

• Application of melanotropin ligands for the treatment of obesity and related disorders

• Targeted drugs in the field of nanomedicine

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, Scilit, EBSCO, Ulrich's Periodicals Directory.

Preface

- Pp. i-iii (3)
Atta-ur-Rahman, M. Iqbal Choudhary, Allen B. Reitz
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Contributors

- Pp. iv
Atta-ur-Rahman, M. Iqbal Choudhary, Allen B. Reitz
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Purinergic Receptors and Pain–An Update

- Pp. 3-55 (53)
Geoffrey Burnstock
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Human Diseases and Mitochondrial Damage: Role of Cytochrome c – Cardiolipin Interaction as a Key Regulator of Cell Fate

- Pp. 56-79 (24)
Roberto Santucci, Federica Sinibaldi, Laura Fiorucci
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Dipeptidyl Peptidase-4 (CD26): Knowing the Function before Inhibiting the Enzyme

- Pp. 80-102 (23)
Elena Matteucci, Ottavio Giampietro
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Peptides Interacting with Growth Factor Receptors Regulating Angiogenesis

- Pp. 103-160 (58)
Rossella Di Stasi, Lucia De Rosa, Alessandra Romanelli, Luca D. D`Andrea
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The Potential Application of Melanotropin Ligands for the Treatment of Obesity and Related Disorders: Potential and Problems

- Pp. 161-181 (21)
Victor J. Hruby, Minying Cai
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Targeted Drugs and Nanomedicine: Present and Future

- Pp. 182-233 (52)
Gudrun C. Thurner, Monika Chabicovsky, Alshaimaa Abdelmoez, Paul Debbage
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Index

- Pp. 234-244 (11)
Atta-ur-Rahman, M. Iqbal Choudhary, Allen B. Reitz
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