Editor: Atta-ur-Rahman

Advances in Cancer Drug Targets

Volume 3

eBook: US $29 Special Offer (PDF + Printed Copy): US $133
Printed Copy: US $119
Library License: US $116
ISSN: 2451-8891 (Print)
ISSN: 2213-9915 (Online)
ISBN: 978-1-68108-234-9 (Print)
ISBN: 978-1-68108-233-2 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810823321160301


Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA.

The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development.

The contents of this volume include reviews on mediating or inhibiting different signaling pathways such as WNT signaling and MTOR as well as novel drug targets for tumor control such as neutrophil elastase and estrogen sulfatase. These reviews provide updates on new ways to treat a variety of cancers.

The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


- Pp. i-ii (2)
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List of Contributors

- Pp. iii-v (3)
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Neutrophil Elastase as a Target in Lung Cancer: the State of the Art

- Pp. 3-49 (47)
Gautier Moroy, Alain J.P. Alix, Janos Sapi, William Hornebeck, Erika Bourguet
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Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack

- Pp. 50-77 (28)
Srinivas Mamidi, Simon Höne, Nicolas Geis, Stefanie Zell, Renate Rutz, Wenhan Li, Thomas Giese, Stefan Schultz, Michael Kirschfink
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Points of Therapeutic Intervention along the Wnt Signaling Pathway in Hepatocellular Carcinoma

- Pp. 78-117 (40)
Miran Kim, Jack R. Wands
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Collaboration of Epithelial Mesenchymal Transition and Cancer Stem Cells: Sinister Routes for Chemoresistant Recurrent Ovarian Cancer

- Pp. 118-155 (38)
N. Ahmed, K. Abubaker, E. Chan, G. Kannourakis, J.K. Findlay
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Oxaliplatin-mediated Inhibition of Survivin Increases Sensitivity of Head and Neck Squamous Cell Carcinoma Cell Lines to Paclitaxel

- Pp. 156-180 (25)
P.S. Bisen, Z. Khan, N. Khan, G.B.K.S. Prasad
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Melatonin Inhibits the Growth of DMBA-induced Mammary Tumors by Regulating Estrogen Sulfatase Enzyme

- Pp. 181-206 (26)
Alicia González, Virginia Álvarez-García, Carlos Martínez-Campa, Carolina Alonso-González, Samuel Cos
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Role of mTOR Signaling in Tumor Cell Motility, Invasion and Metastasis

- Pp. 207-244 (38)
Hongyu Zhou, Shile Huang
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Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors

- Pp. 245-264 (20)
Sonia Colombo, Alessandro Palmioli, Cristina Airoldi, Renata Tisi, Sonia Fantinato, Sandro Olivieri, Luca De Gioia, Enzo Martegani, Francesco Peri
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Subject Index

- Pp. 265-266 (2)
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.Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach.
.The Management of Metastatic Triple-Negative Breast Cancer: An Integrated and Expeditionary Approach.
.Cancer Medicine in an Ayurvedic Perspective: A Critical Overview.
.Cancer Genes.