Editor: Ahmed El-Hashash

Developmental and Stem Cell Biology in Health and Disease

eBook: US $39 Special Offer (PDF + Printed Copy): US $138
Printed Copy: US $119
Library License: US $156
ISBN: 978-1-68108-220-2 (Print)
ISBN: 978-1-68108-219-6 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810821961160101


Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the implantation stage in utero to the regulation of stem cell division. Medical applications of stem cells in the therapy of diseases such as cancer, neurodegenerative diseases, and bone diseases are also explained in subsequent chapters. The book also explains the effect of parasitic cells on stem cell growth. Concepts in the book are explained in a simple clear manner, making this book an informative reference for non-experts, students and professionals in the field of biology and medicine.


- Pp. i
Ahmed El-Hashash
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List of Contributors

- Pp. ii-iii (2)
Ahmed El-Hashash
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Stem Cells, Developmental Biology and Reparative/ Regenerative Medicine: Tools and Hope for Better Human Life

- Pp. 3-5 (3)
Ahmed El-Hashash
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The First Morphogenetic Events During Mammalian Development

- Pp. 6-35 (30)
Manal E. Elsawaf
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Gene and Signals Regulating Stem Cell Fates

- Pp. 36-48 (13)
Mohamed Berika, John Ku, Haifen Huang, Ahmed El-Hashash
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Stem Cell Biology: Flies As Models and Examples

- Pp. 49-81 (33)
Nahla M. Shoukry, Elham M. Youssef Elabd, Hani S. Hafez, Noha M. Osman
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Behavior and Asymmetric Cell Divisions of Stem Cells

- Pp. 82-105 (24)
Sameh Elshahawy, Ahmed R. N. Ibrahim, Salaheldin S. Soliman, Marwa E. Elgayyar, Ahmed El-Hashash
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Adult Stem Cell Niches and Their Regulatory Molecular Mechanisms

- Pp. 106-120 (15)
John Ku, Wadah Alhassen, Haifen Huang, Salaheldin S. Soliman, Ahmed RN Ibrahim, Ahmed HK El-Hashash
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Stem Cell Regulatory Mechanisms During Wound Healing and Cancer

- Pp. 121Chapter-142 (22)
Ahmed RN Ibrahim, Deshna Majmudar, Safia Gilani, Jesse Garcia Castillo, Ahmed El-Hashash
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Stem Cells in Cancer Development and Therapy

- Pp. 143-165 (23)
Azza El Amir, Wajeet Nabil
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Stem Cells and Neurodegenerative Diseases

- Pp. 166-192 (27)
Hanaa H. Ahmed, Hadeer A. Aglan, Ahmed A. Abd-Rabou
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Stem Cells and Bone Disorders

- Pp. 193-209 (17)
Hanaa H. Ahmed, Sara M. Abdo, Ahmed A. Abd-Rabou
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A Scope on Stem Cells and Human Parasites

- Pp. 210-247 (38)
Marwa Adel HasbySaad
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Subject Index

- Pp. 248-249 (2)
Ahmed El-Hashash
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.Stem Cells in Clinical Application and Productization.
.Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications.
.The Regeneration Promise: The Facts behind Stem Cell Therapies.
.Vascularization in Tissue Engineering.