Recently, we showed that reduced adiponectin levels were associated with multi-vessel coronary artery atherosclerosis as detected on computed tomography coronary angiography (CTCA), and adiponectin may be a useful biomarker to predict multivessel coronary atherosclerosis when detected using CTCA in combination with common risk factors including age, sex, DM, and hypertension. Moreover, in another study, we showed that reduced adiponectin levels were associated with elevated serum oxidized low-density lipoprotein levels in which dyslipidemic components of metabolic syndrome were strongly involved. Thus, adiponectin levels are associated directly and indirectly with the development of atherosclerosis.
Measuring adiponectin concentration should provide beneficial information for the selection of high-risk patients and contribute to the reduction of fatal CAD by applying aggressive preventive therapy.
Total Pages: 173-187 (15)
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