Author: Robert E. Smith

Medicinal Chemistry - Fusion of Traditional and Western Medicine, Second Edition

eBook: US $89 Special Offer (PDF + Printed Copy): US $217
Printed Copy: US $173
Library License: US $356
ISBN: 978-1-60805-975-1 (Print)
ISBN: 978-1-60805-974-4 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080597441140201


Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking. Readers will learn about how new drugs are investigated, developed and eventually approved by the FDA. The book also includes important information about cGMP, GLP and the FDA regulatory requirements, the importance of environmental toxins, such as bisphenol A (BPA) and perfluorooctanoic acid (PFOAA) in autoimmune diseases and health. This book offers exceptional value in its descriptions of RNA, epigenetics, toxicology, new drug development, genetically modified organisms and analytical chemistry that cannot be found in other textbooks.

Indexed in: Book Citation Index, Science Edition, EBSCO.


As a practicing physician, I found this second edition to be very up-to-date, interesting and useful. It would be an excellent text book for the first semester in the standard two-semester course taught at most pharmacy schools. Much of it describes concepts and metabolic processes for which there was limited knowledge or was completely unknown when I was a medical student. The information presented provides undergraduate, medical and pharmacy students with useful information about the indications for and applications of modern medicinal chemistry. It will also help currently licensed physicians prepare for Board certification and recertification. Many of the old questions may have new answers. For example, 30 years ago, it was believed that genetic information could flow only from DNA to RNA to proteins, or that patients could not have an autoimmune disease. Thirty years ago the correct answers would have been yes – now they are no! I also found the book to be very helpful in describing medicines that I currently prescribe to patients and new drugs that are being developed. On frequent occasions, a patient will ask, “Why aren’t doctors doing more to find cures for common diseases”. The information in this book provides useful answers. I am also frequently asked questions about nutrition, dietary supplements and environmental toxins. The information about these subjects was written in clear, simple language that most people can understand. Other important and useful information regards the environmental toxin and endocrine disruptor, bisphenol A, or BPA. The popular literature and mass media debate whether microgram quantities of BPA in plastic products are harmful, but they ignore the milligram quantities of BPA that are found in most receipts that you get from ATM machines and cash registers. It is especially important to not let infants put such paper in their mouths as they explore the world orally or make spit wads in school as adolescents. It could harm their reproductive development. So, the book is very readable and has a multi-disciplinary approach. It teaches the kind of things that I would like to see medical and pharmacy students learn and could even be useful to lay people.

Mark D. Pilley
NE 68124-3135