Author: Robert E. Smith

Medicinal Chemistry - Fusion of Traditional and Western Medicine, Second Edition

eBook: US $89 Special Offer (PDF + Printed Copy): US $217
Printed Copy: US $173
Library License: US $356
ISBN: 978-1-60805-975-1 (Print)
ISBN: 978-1-60805-974-4 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080597441140201

Introduction

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking. Readers will learn about how new drugs are investigated, developed and eventually approved by the FDA. The book also includes important information about cGMP, GLP and the FDA regulatory requirements, the importance of environmental toxins, such as bisphenol A (BPA) and perfluorooctanoic acid (PFOAA) in autoimmune diseases and health. This book offers exceptional value in its descriptions of RNA, epigenetics, toxicology, new drug development, genetically modified organisms and analytical chemistry that cannot be found in other textbooks.

Indexed in: Book Citation Index, Science Edition, EBSCO.

Foreword

- Pp. i
Mark D. Pilley
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Preface

- Pp. ii
Robert E. Smith
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Introduction

- Pp. 3-108 (106)
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Biotechnologies for Medicinal Chemists

- Pp. 109-127 (19)
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Developing New Drugs

- Pp. 128-162 (35)
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How New Drugs Are Developed: Kinetics Evaluations

- Pp. 163-222 (60)
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How New Drugs Are Developed: Toxicology

- Pp. 223-251 (29)
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How New Drugs Are Developed: Improve the Lead Compound

- Pp. 252-272 (21)
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How New Drugs Are Developed: Drug Delivery

- Pp. 273-282 (10)
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How New Drugs Are Developed: Manufacturing and cGMP

- Pp. 283-329 (47)
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How New Drugs Are Investigated

- Pp. 330-341 (12)
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Drugs That Inhibit Enzymes

- Pp. 342-389 (48)
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Drugs That Interact with Receptors and Ion Channels

- Pp. 390-415 (26)
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Drugs That Target Transporters, Carriers and Ion Pumps

- Pp. 416-424 (9)
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Drugs That Act on Microtubules

- Pp. 425-451 (27)
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Drugs That Target or Use DNA or RNA

- Pp. 452-468 (17)
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Appendix

- Pp. 469-536 (68)
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Subject Index

- Pp. 537-545 (9)
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