Editors: Atta-ur-Rahman , M. Iqbal Choudhary , Jizhou Wang, Allen B. Reitz

Frontiers in Medicinal Chemistry

Volume 7

eBook: US $190 Special Offer (PDF + Printed Copy): US $285
Printed Copy: US $190
Library License: US $760
ISSN: 1567-2042 (Print)
ISSN: 1875-5763 (Online)
ISBN: 978-1-60805-971-3 (Print)
ISBN: 978-1-60805-970-6 (Online)
Year of Publication: 2015
DOI: 10.2174/97816080597061150701

Introduction

“Frontiers in Medicinal Chemistry” is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. “Frontiers in Medicinal Chemistry” covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. Medicinal chemistry as a discipline is rapidly maturing. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. “Frontiers in Medicinal Chemistry” aims to contribute in a major way to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. This Ebook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

Preface

This current Volume 7 of Frontiers in Medicinal Chemistry is comprised of 11 chapters written by the appropriate experts in their fields of study, focusing on topics of high important in the fields of medicinal chemistry, early-stage drug discovery, target validation, and chemical biology.

The first six manuscripts are focused on topics of interest to diseases of the central nervous system. The first by Kaur et al. is on antioxidants and neuroprotection, the second by Munoz-Torrero is on acetylcholinesterase inhibitors for Alzheimer’s disease, the third by Ferrari-Toninelli et al. covers dopamine agonists for Parkinson’s disease, the fourth by Marassiti et al. highlights the role of oxytocin in psychiatry, the fifth by Fernandez-Busquets et al. pertains to the many proteins for which inappropriate conformation contributes to pathology such as Alzheimer’s, and the sixth by Loizzo et al. covers natural-product based cholinesterase inhibitors, also for Alzheimer’s disease. The next three reviews are in the area of infectious disease research, the first by Abbat et al. on enzyme inhibitors for the treatment of malaria, the second by Fabbri et al. on bacterial protein toxins, and the third by Sciutto et al. on a vaccine approach to cysticercosis. The next review is on liver fibrosis by Zardi, and the final chapter is by Jiang et al. on regenerative engineering.

Thanks are given to the staff of Bentham Science Publishers for their support and guidance, particularly Drs. Mahmood Alam and Matthew Honan.

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA 18902
USA


Atta-ur-Rahman, FRS
Kings College
University of Cambridge
Cambridge
UK


Iqbal Choudhary
H.E.J. Research Institute of Chemistry
University of Karachi, Karachi 75270
Pakistan


&

Jizhou Wang
Silver Spring, MD,USA
USA


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