Editors: Lutfi A. Jaber, Gabrielle J. Halpern

Consanguinity – Its Impact, Consequences and Management

Special Offer (PDF + Printed Copy): US $106
Printed Copy: US $106
ISBN: 978-1-60805-889-1 (Print)
ISBN: 978-1-60805-888-4 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080588841140101

Introduction

Consanguineous marriages have been practiced for hundreds of years, predominantly by Moslems. Although it is generally accepted among communities that the social advantages outweigh other, the rate of congenital malformations and genetic diseases among the offspring borne of consanguineous marriages is higher and an increase in sterility, rates of abortions, stillbirths and neonatal deaths has been suggested by some researchers. These problems result in a substantial economic burden within the communities involved in the practice. Strategies for reducing the frequency of consanguineous marriages include expansion of educational programs, promotion of genetic testing services, and research to identify the genes responsible for genetic defects. Nowadays, with the migration of large numbers of Moslems towards Western countries, consanguinity is becoming a practical issue in places where it was barely known, previously. This eBook serves as a guide for health care workers and counselors of the phenomenon and its associated problems. This eBook begins with an introduction of the topic from a social, legal and biological perspective. It then progresses to research about associated genetic disorders, reproductive and social awareness issues through the proceeding chapters. The eBook concludes with 2 chapters exploring strategies to counter the effects of consanguinity within the general population.

Contributors

Editor(s):
Lutfi A. Jaber
Tel Aviv University
Tel Aviv
Israel


Gabrielle J. Halpern
The Raphael Recanati Genetic Institute
Petah Tikva
Israel




Contributor(s):
Hagit N. Baris
The Genetic Institute
Rambam Health Care Campus, P.O. Box 9602
Haifa, 3109601
Israel


Lina Basel-Vanagaite
Pediatric Genetics Unit
Schneider Children's Medical Center of Israel
14 Kaplan St.
Petah Tikva, 49202
Israel
/
The Raphael Recanati Genetic Institute
Rabin Medical Center, Beilinson Hospital
Petah Tikva, 49100
Israel
/
Felsenstein Medical Research Center
Rabin Medical Center
Petah Tikva, 49100
Israel
/
Sackler Faculty of Medicine
Tel Aviv University
Tel Aviv, 69978
Israel


Gabrielle J. Halpern
The Raphael Recanati Genetic Institute
Rabin Medical Center
Beilinson Hospital
Petah Tikva, 49100
Israel


Lutfi A. Jaber
The Bridge to Peace Community Pediatric Center
Taibe, 40400
Israel
/
Institute of Neurology
Schneider Children's Medical Center of Israel
14 Kaplan St.
Petah Tikva, 49202
Israel
/
Sackler Faculty of Medicine
Tel Aviv University
Tel Aviv, 69978
Israel


Wen-Hann Tan
Division of Genetics
Boston Children's Hospital
300 Longwood Avenue
Boston
MA, 02115
USA
/
Department of Pediatrics
Harvard Medical School
25 Shattuck Street
Boston
MA, 02115
USA




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