Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research-Hematology

Volume 1

eBook: US $39 Special Offer (PDF + Printed Copy): US $147
Printed Copy: US $128
Library License: US $156
ISSN: 2467-9585 (Print)
ISSN: 2352-3239 (Online)
ISBN: 978-1-60805-859-4 (Print)
ISBN: 978-1-60805-858-7 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080585871140101


Frontiers in Clinical Drug Research – Hematology is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.

The first volume of this series features 6 chapters that cover a variety of topics including:

  • - Computational methods, molecular docking, and molecular dynamics simulation
  • - Recent advances in the treatment of Beta-Thalassemia Major
  • - Research on multiple myeloma and leukemia
  • - Molecular imaging in hematology


- Pp. i-ii (2)
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List of Contributors

- Pp. iii-iv (2)
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Is a Protective Microenvironment the “Achille’s Heel” in Chronic Lymphocytic Leukemia?

- Pp. 3-41 (39)
Paolo Giannoni, Daniela de Totero
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Epigenetic Drugs in Myelodysplastic Syndrome and the Leukemias

- Pp. 42-61 (20)
Jacob Peedicayil
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Myeloproliferative Neoplasms – Molecular Biology and Potential Targets for Intervention

- Pp. 62-102 (41)
Martin H. Bonamino, Barbara Monte-Mor, Cristiana Solza, Ilana Zalcberg
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Thalidomide, Bortezomib and Lenalidomide – Three Drugs that Changed Multiple Myeloma

- Pp. 103-178 (76)
Jiri Minarik, Vlastimil Scudla
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Application of Molecular Imaging for Drug Discovery and Development in Hematology Research

- Pp. 179-224 (46)
Pengfei Xu, Min Liu, Xiaobo Wang, Zhiguo Liu, Weimin Miao, Wenbin Zeng
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Recent Advances in the Treatment of β-Thalassemia Major

- Pp. 225-276 (52)
Manju Mamtani, Hemant Kulkarni
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Integrating Computational Methods, Molecular Docking, and Molecular Dynamics Simulation Approaches Towards Personalized Medicine in Hematological Disorders

- Pp. 277-325 (49)
George Priya Doss C, Chiranjib Chakraborty
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Treatment with Acetylsalicylic Acid in Neurological Disorders – Old Drug, New Uses

- Pp. 326-362 (37)
Maria Lukasik, Slawomir Michalak
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- Pp. 363-378 (16)
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