Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research- Central Nervous System

Volume 1

eBook: US $79 Special Offer (PDF + Printed Copy): US $158
Printed Copy: US $119
Library License: US $316
ISSN: 2467-9623 (Print)
ISSN: 2214-6318 (Online)
ISBN: 978-1-60805-780-1 (Print)
ISBN: 978-1-60805-779-5 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080577951130101

Introduction

Frontiers in Clinical Drug Research – Central Nervous System presents the latest research and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals.

The first volume of the series features chapters on the following topics:

-Nerve targets in pain medicine

-Spinal cord injury

-Research on neurotoxins targeting voltage gated ion channels

-G protein coupled receptor agonists and modulators

-Drug research on mediating hypoxia in developing white matter

Foreword

- Pp. i
Ferid Murad
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Preface

- Pp. ii-iii (2)
Atta-ur-Rahman
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List of Contributors

- Pp. iv-v (2)
Atta-ur-Rahman
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Agonists and Allosteric Modulators of G Protein-Coupled Receptors as Promising Psychotropic Drugs

- Pp. 3-43 (41)
Yuji Odagaki

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Central Glia as Prospective Targets in Chronic Pain

- Pp. 44-60 (17)
Romain-Daniel Gosselin

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Spinal Cord Injury: Clinical Trials and Translational Tribulations

- Pp. 61-99 (39)
Simon Harris, Jared Wilcox and Michael G. Fehlings

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Peptide Neurotoxins Targeting Voltage-Gated Ion Channels and Their Therapeutic Implications

- Pp. 100-165 (66)
Seungkyu Lee and Sun W. Hwang

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Drugs Targeting Microglial Activation in Hypoxic Damage to the Developing White Matter

- Pp. 166-228 (63)
Gurugirijha Rathnasamy, Madhuvika Murugan, Eng-Ang Ling and Charanjit Kaur

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Index

- Pp. 229-245 (17)
Atta-ur-Rahman
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