Editors: Atta-ur-Rahman, Iqbal Choudhary

Frontiers in CNS Drug Discovery

Volume 2

eBook: US $89 Special Offer (PDF + Printed Copy): US $202
Printed Copy: US $158
Library License: US $356
ISSN: 1879-6656 (Print)
ISSN: 1879-6613 (Online)
ISBN: 978-1-60805-768-9 (Print)
ISBN: 978-1-60805-767-2 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080576721130201


“Frontiers in CNS Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in CNS drug design and discovery. Each volume is devoted to the major advances in CNS drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.


- Pp. i-iv (4)
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List of Contributors

- Pp. v-vii (3)
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Developing Treatments for Prion Diseases and Implications for Other Protein Misfolding Disorders

- Pp. 3-25 (23)
Brian S. Appleby
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Epigenetic Modifications as Novel Targets for Drug Addiction

- Pp. 26-42 (17)
Candace R. Lewis, Michael F. Olive
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Manipulation of Endogenous Neural Stem Cells as a Therapeutic Strategy for Neurodegenerative Diseases: Insights from Animal Models

- Pp. 43-79 (37)
Anna Patten, Patricia S. Brocardo, Joana M. Gil-Mohapel
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New Therapies for HIV-1-Associated Neurocognitive Disorder (HAND): Animal Models and Gene Delivery of Antioxidant Enzymes by rSV40

- Pp. 80-117 (38)
Jean-Pierre Louboutin, David S. Strayer
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Transient Receptor Potential Ion Channels as Promising Therapeutic Targets: An Overview

- Pp. 118-145 (28)
Merab G. Tsagareli
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Antipsychotic Polypharmacy in Schizophrenia, from Empirical Associations to Combined Selective Treatments

- Pp. 146-210 (65)
Alessandro De Risio, Davide Carlino
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The Role of Natural Products on the Discovery of New Drug Candidates for Neurogenerative Disorders

- Pp. 211-280 (70)
Flávia P.D. Viegas, Rodolfo do C. Maia, Roberta Tesch, Carlos A.M. Fraga, Claudio Viegas
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Flavonoids – Their Preventer and Therapeutic Applications Against Parkinson’s Disease

- Pp. 281-311 (31)
Elena González-Burgos, Maria P. Gómez-Serranillos
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Essential Polyunsaturated Fatty Acids as New Treatments for Neurodegenerative Diseases

- Pp. 312-333 (22)
Cai Song
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Application of Monoterpenoids and their Derivatives Against CNS Disorders

- Pp. 334-380 (47)
Alla V. Pavlova, Konstantin P. Volcho, Tatyana G. Tolstikova
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Use of Zebrafish to Identify New CNS Drugs Acting Through Nicotinic and Dopaminergic Systems

- Pp. 381-406 (26)
Robert T. Boyd
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- Pp. 407-423 (17)
Atta-ur-Rahman, M. Iqbal Choudhary
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