Editor: Christian Neri

Series Title: Advances in Genome Science

Probing Intracellular Regulation

Volume 2

eBook: US $39 Special Offer (PDF + Printed Copy): US $138
Printed Copy: US $119
Library License: US $156
ISSN: 2452-3690 (Print)
ISSN: 2213-6606 (Online)
ISBN: 978-1-60805-757-3 (Print)
ISBN: 978-1-60805-756-6 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080575661130201

Introduction

Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essentiality and diversity of genomics in contemporary science.

The second volume of this ebook series contains a selection of articles on intracellular gene regulation and expressoion in human disease such as arthritis, Alzheimer’s disease, Nijmegen Breakage Syndrome, Tumors and Malaria among other diseases. The volume also features some chapters on plant genetics.

Preface

- Pp. i
Christian Neri
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List of Contributors

- Pp. ii-v (4)

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Pharmacogenetics of Rheumatoid Arthritis and Spondyloarthropathies

- Pp. 3-27 (25)
Ignacio Rego-Pérez, Natividad Oreiro-Villar, Carlos Fernández-López, Jose-Luis Fernández-Sueiro, Francisco J. Blanco
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One-Carbon Metabolism and Alzheimer’s Disease: The DNA Methylation Hypothesis

- Pp. 28-76 (49)
Fabio Coppedè
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Mechanisms and Signals for the Nuclear Import of Proteins

- Pp. 77-100 (24)
Natália Freitas, Celso Cunha
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Cancer Proneness in Nijmegen Breakage Syndrome Carriers

- Pp. 101-119 (19)
Alessandra di Masi, Francesco Berardinelli, Domenica Cilli, Antonio Antoccia
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Alternative Splicing and Tumor Progression

- Pp. 120-154 (35)
Claudia Ghigna, Cristina Valacca, Giuseppe Biamonti
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Role of HMGB Proteins in Coordinating Ribosomal Protein and Ribosomal RNA

- Pp. 155-175 (21)
LiJuan Xiao, Anne Grove
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Databases and Web-Tools for Gene Expression Analysis in Arabidopsis thaliana

- Pp. 176-193 (18)
Reinhard Hehl, Julio C. Bolívar, Jeannette Koschmann, Yuri Brill, Lorenz Bülow
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Genetical Genomics of Plants: From Genotype to Phenotype

- Pp. 194-220 (27)
Ronny V.L. Joosen, Wilco Ligterink, Henk W.M. Hilhorst, Joost J.B. Keurentjes
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Expanded CTG Repeat Induced Molecular Alterations in Myotonic Dystrophy

- Pp. 221-245 (25)
Beatriz Llamusí, Ariadna Bargiela, Ruben Artero
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Saturation of the Human Phenome

- Pp. 246-296 (51)
Mark E. Samuels
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Malaria Functional Genomics and Beyond

- Pp. 297-323 (27)
Jianbing Mu, Karl B. Seydel, Adam Bates, Junhui Duan, Lubin Jiang, Xin-zhuan Su
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Index

- Pp. 324-335 (12)
Christian Neri
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