Editor: " Atta-ur-Rahman"

Advances in Cancer Drug Targets

Volume 1

Personal Book: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $119
Library Book: US $356
ISSN: 2451-8891
eISSN: 2213-9915 (Online)
ISBN: 978-1-60805-601-9
eISBN: 978-1-60805-474-9 (Online)
DOI: 10.2174/97816080547561130101

Introduction

Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.

Foreword

- Pp. i- (1)
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List of Contributors

- Pp. ii-v (4)
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The PIK3CA Gene as a Mutated Target for Cancer Therapy

- Pp. 3-21 (19)
Sarah Croessmann, Justin Cidado, John P. Gustin, David Cosgrove and Ben Ho Park

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AKT Signaling in Regulating Angiogenesis

- Pp. 22-50 (29)
Bing-Hua Jiang and Ling-Zhi Liu

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Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment (An Update)

- Pp. 51-119 (69)
P. Sapra Sharma and R. Sharma

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Cellular FLICE-Like Inhibitory Protein (c-FLIP): A Key Anti- Apoptotic Factor and a Target for Cancer Therapy

- Pp. 120-145 (26)
Ahmad R. Safa

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Pin1: A Promising Novel Diagnostic and Therapeutic Target that Acts on Numerous Cancer-Driving Pathways

- Pp. 146-171 (26)
Greg Finn, Man-Li Luo, Xiao Zhen Zhou and Kun Ping Lu

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Anticancer Immunotherapy in Combination with Proapoptotic Therapy - Possible Therapeutic Strategies for Enhancement of Anticancer Immune Reactivity in Autologous Immunocompetent Cells and After Allogeneic Stem Cell Transplantation

- Pp. 172-206 (35)
Håkon Reikvam, Elisabeth Ersvær, Guro Kristin Melve, Astrid Olsnes Kittang, Bjørn Tore Gjertsen and Øystein Bruserud

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Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions

- Pp. 207-237 (31)
Samuel Cos, Alicia González, Virginia Alvarez-García, Carolina Alonso-González and Carlos Martínez-Campa

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Targeting Cancer and Neuropathy with Histone Deacetylase Inhibitors

- Pp. 238-263 (26)
V. Rodriguez-Menendez, L. Tremolizzo and G. Cavaletti

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Index

- Pp. 264-308 (45)
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