Editor: Qing Qiao

Epidemiology of Type 2 Diabetes

eBook: US $29 Special Offer (PDF + Printed Copy): US $121
Printed Copy: US $107
Library License: US $116
ISBN: 978-1-60805-529-6 (Print)
ISBN: 978-1-60805-361-2 (Online)
Year of Publication: 2012
DOI: 10.2174/97816080536121120101

Introduction

This e-book on diabetes epidemiology starts with the evolution in the diagnostic criteria for diabetes, particularly the changes in the last 15 years and their impact on the prevalence of the disease. The increasing trend in prevalence of diabetes worldwide, and its impact on people’s health and economic development are described by regions and countries. The rationale for a diabetes screening program, recent development in screening strategies and screening tools are thoroughly reviewed and presented. Because obesity is one of the major risk factors for diabetes and has been included in several risk assessment questionnaires, the obesity-diabetes association is particularly addressed in this e-book. The diagnostic cut-off value for surrogate measurement of body fat mass such as body mass index (BMI) and waist circumference is also discussed. The measurement errors and the strength of the association of diabetes with BMI and waist circumference are formally compared. Other diabetes related metabolic disorders such as dyslipidemia and hyperuricemia are also discussed with regard to their association with different degree of glucose intolerance including pre-diabetes and undiagnosed diabetes. The risk of dyslipidemia with cardiovascular mortality and morbidity in people with different glucose levels is estimated within different ethnic groups and the ethnic differences are compared. Recent interest on diabetes-cancer association is on the rise. Academic literature on this issue presented in this volume. The relationship of diabetes with cardiovascular disease is also recognised. In this book the focus is set on the impact of various levels of fasting and 2-hout post-load glucose on the occurrence of cardiovascular mortality and morbidity.

Preface

The idea of the eBook took shape in the editor’s mind in 2010 when several co-authors of the eBook completed a series of doctorial theses covering a wide range of research topics on epidemiology of type 2 diabetes. Each of the theses comprises not only a comprehensive literature review and meta-analysis but also the author’s own research results, which are mainly based on a well recognized large international collaborative study in Europe and Asia---the Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe (DECODE) and Asia (DECODA) study. The authors, each at the forefront of his/her research field, have updated and dedicated their works to the eBook with aims to share their research outcomes with more people who are interested in doing epidemiological researches on diabetes, and to help the young researchers to understand easily the progress and the significant development in the relevant fields during the past decades.

This eBook consisting of eight chapters covers the frontiers of works on evolution of diagnostic criteria, prevalence of diabetes, screening programs and tools for early detection of type 2 diabetes, developing and evaluation of risk assessment algorithms, obesity and diabetes, anthropometric measures of obesity and its validity in predicting diabetes, comparison between central and general obesity, lipid levels in relation to glucose tolerance status, uric acid and diabetes, relationship of cancer with diabetes and non-diabetic hyperglycemia, cardiovascular disease in relation to diabetes and non-diabetic glycemic levels including outcomes from the recent randomized controlled clinical trials that have investigated the effect of intensive glycemic control on cardiovascular disease outcomes. The ethnic differences in the association of diabetes with obesity, dyslipidemia and other metabolic disorders have been extensively investigated in the DECODE/DECODA study and the interesting findings are included in this eBook, which are the most important original works of the authors.

Qing Qiao
University of Helsinki
Finland

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