Frontiers in Drug Design and Discovery

Volume 2

eBook: US $44 Special Offer (PDF + Printed Copy): US $195
Printed Copy: US $173
Library License: US $176
ISSN: 1574-0889 (Print)
ISSN: 2212-1064 (Online)
ISBN: 978-1-60805-670-5 (Print)
ISBN: 978-1-60805-200-4 (Online)
Year of Publication: 2006
DOI: 10.2174/97816080520041060201


Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The book series should prove to be of interest to all the pharmaceutical scientists involved in research in drug design and discovery. Each volume is devoted to the major advances in drug design and discovery.

The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The book series is available in print, online and CD editions.

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EMBASE, Scopus, Genamics JournalSeek

Indexed in: Scopus, EMBASE, EBSCO, Ulrich's Periodicals Directory.

Editorial: Biomarkers to Biosensors - Technologies and Applications to Improve the Drug Discovery Process

- Pp. i-iii (3)
Gary W. Caldwell, Atta-ur-Rahman, Michael R. D`Andrea, M. Iqbal Choudhary
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Strategies of Biomarker Discovery for Drug Development

- Pp. 5-22 (18)
Xiang Jian Lou, S. M. Belkowski, James M. Dixon, Brenda Hertzog, Dan Horowitz, Sergey I. Ilyin, Danielle Lawrence, D. Polkovit
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Protein and Antibody Microarrays: Clues Towards Biomarker Discover

- Pp. 23-33 (11)
Kazue Usui-Aoki, Motoki Kyo, Makoto Kawai, Masatoshi Murakami, Kazuhide Imai, Kiyo Shimada, Hisashi Koga
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The Use of Biomarkers to Detect Cervical Neoplasia and to Diagnose High-Grade Cervical Disease

- Pp. 35-54 (20)
Douglas P. Malinowski
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New Developments in the Field of Protein and Metabolism Assays Aimed at Drug Discovery Processes

- Pp. 55-86 (32)
Kothandaraman Narasimhan, Ponnusamy Sukumar, Mahesh Choolani
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Proteomic Screening for Novel Therapeutic Targets in Kidney Diseases

- Pp. 87-102 (16)
Visith Thongboonkerd
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Aptamer-Based Technologies as New Tools for Proteomics in Diagnosis and Therapy

- Pp. 103-119 (17)
Vittorio de Franciscis, Laura Cerchia
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Recent Developments in Proteomics: Mass Spectroscopy and Protein Arrays

- Pp. 121-150 (30)
Aarohi Kulkarni, Mala Rao
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NMR Spectroscopy Based Metabonomics: Current Technology and Applications

- Pp. 151-173 (23)
Clare A. Daykin, Florian Wulfert
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NMR-Based Metabonomics of Urine from An Exploratory Study of Ciprofibrate in Healthy Volunteers and Patients with Type 2 Diabete

- Pp. 175-191 (17)
Gregory C. Leo, Ewoud J. van Hoogdalem, Martijn B.A. van Doorn
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Chromatography Mass Spectrometry Based Metabonomic Analytical Methods

- Pp. 193-209 (17)
Gary W. Caldwell, Wensheng Lang, Gregory C. Leo, John A. Masucci, William Jones, Andrew Mahan
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OWLS - A Versatile Technique for Drug Discovery

- Pp. 211-223 (13)
Jeremy J. Ramsden
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Cell-Based Biosensors in Proteomic Analysis

- Pp. 225-239 (15)
Spiridon E. Kintzios
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Current Approaches in Natural Biopolymer- Nanoparticle Hybrid Functional Materials: From Drug Delivery to Bio-Detection Applicat

- Pp. 241-258 (18)
Roberta Brayner
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Spectroscopic Analysis of Cell Physiology and Function

- Pp. 259-272 (14)
Mark Riley, Iram Mondaca Fernandez, Pierre Lucas
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Encapsulated Biomolecules Using Sol-Gel Reaction for High-Throughput Screening

- Pp. 273-294 (22)
Kumiko Sakai-Kato, Masaru Kato, Naoko Utsunomiya-Tate, Toshimasa Toyo`oka
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Modeling of Environmentally Sensitive Hydrogels for Drug Delivery: An Overview and Recent Developments

- Pp. 295-331 (37)
Hua Li, Rongmo Luo, K.Y. Lam
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Polyelectrolyte Nanocapsules - Promising Progress in Development of New Drugs and Therapies

- Pp. 333-348 (16)
Silke Krol, Alessandra Gliozzi, Alberto Diaspro
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- Pp. 349-352 (4)
Atta-ur-Rahman, Gary W. Caldwell, M. Iqbal Choudhary, Michael R. D’Andrea
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Subject Index to Volume 2

- Pp. 353-365 (13)
Atta-ur-Rahman, Gary W. Caldwell, M. Iqbal Choudhary, Michael R. D’Andrea
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