Frontiers in Drug Design and Discovery

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $189
Printed Copy: US $167
Library License: US $176
ISSN: 1574-0889 (Print)
ISSN: 2212-1064 (Online)
ISBN: 978-1-60805-669-9 (Print)
ISBN: 978-1-60805-199-1 (Online)
Year of Publication: 2005
DOI: 10.2174/97816080519911050101

Introduction

Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The book series should prove to be of interest to all the pharmaceutical scientists involved in research in drug design and discovery. Each volume is devoted to the major advances in drug design and discovery.

The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The book series is available in print, online and CD editions.

Indexed in

EMBASE, Scopus, Genamics JournalSeek

Indexed in: Scopus, EMBASE, EBSCO, Ulrich's Periodicals Directory.

Editorial: Cutting Edge Tools in Drug Discovery

- Pp. i-ii (2)
Garry W. Caldwell, Atta-ur-Rahman and Barry A. Springer
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Discovering Novel Antibacterial Agents by High Throughput Screening

- Pp. 3-16 (14)
Stefano Donadio, Letizia Brandi, Stefania Serina, Margherita Sosio and Sofia Stinchi
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Small Molecule Drug Targeting of RNA

- Pp. 17-28 (12)
Guido J.R. Zaman

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Drug Discovery and Design Via High Throughput Screening of Combinatorial Phage-Display Protein- Peptide Libraries

- Pp. 29-67 (39)
Karlen Gazarian

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High Throughput Screening: Will The Past Meet The Future?

- Pp. 69-86 (18)
Patrick Englebienne

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Variety of the DNA Hybridization Rate and Its Relationship with High Order Structure of Single Stranded Nucleic Acids

- Pp. 87-96 (10)
Makoto Tsuruoka

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An Overview of High Throughput Screening at G Protein Coupled Receptors

- Pp. 97-111 (15)
Richard M. Eglen
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Developments in Hyphenated Spectroscopic Methods in Natural Product Profiling

- Pp. 113-166 (54)
Sylvia Urban and Frances Separovic

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The Role of Kinetics in High Throughput Screening for Drugs

- Pp. 167-195 (29)
Agustina Gomez-Hens and M Paz Aguilar-Caballos

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Assessment of iDEA pkEXPRESS™ for The Prediction of Caco-2 Permeabilities

- Pp. 197-209 (13)
Cheng-Pang (Matt) Hsu, Garry W. Caldwell, John A. Masucci, Zhengyin Yan and David M. Ritchie

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Exploring the Viability of Metabonomic Urinalysis as a Toxicity Screen Within a Pharmaceutical Drug Discovery Division

- Pp. 211-229 (19)
Gregory C. Leo, Gary W. Caldwell, William Hageman, Becky Hastings, Beata Starosciak, Kristin Snyder, Jaclyn Scowcroft and Aaron Kri

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Partition of Solvents and Co-Solvents of Nanotubes: Proteins and Cyclopyranoses

- Pp. 231-266 (36)
Francisco Torrens

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Automating Literature-Based Lead Discovery

- Pp. 267-286 (20)
Jonathan D. Wren

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Structural Biology in Early Phase Drug Discovery

- Pp. 287-296 (10)
Richard Alexander and John Spurlino

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Whole Gene Synthesis: A Gene-O-Matic Future

- Pp. 297-341 (45)
Lance Stewart and Alex B. Burgin

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Contributors

- Pp. 343-345 (3)
Garry W. Caldwell and Atta-ur-Rahman
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Subject Index

- Pp. 347-360 (14)
Garry W. Caldwell and Atta-ur-Rahman
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