Editors: Atta-ur-Rahman, M.Iqbal Choudhary

Anti-Obesity Drug Discovery and Development

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $168
Printed Copy: US $146
Library License: US $176
ISSN: 2467-9615 (Print)
ISSN: 2210-2698 (Online)
ISBN: 978-1-60805-584-5 (Print)
ISBN: 978-1-60805-163-2 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080516321110101

Introduction

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs.

Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. Fifteen well written reviews make this special volume an excellent compilation of recent developments in anti-obesity treatment. The reviews cover a variety of topics including the development of specific, safe and effective receptor antagonists, the role of epithelial endocrine cells and post operative treatment strategies. This book should be useful to clinicians and medicinal chemists involved in ant-obesity research and therapy.

Indexed in: Scopus, Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

Contributors

Editor(s):
Prof. Dr. Atta-ur-Rahman FRS
University of Karachi
Pakistan


Prof. Dr. M.Iqbal Choudhary
University of Karachi
Pakistan




Contributor(s):
Ya-Wen Hsu
Department of Physical Medicine and Rehabilitation, Taipei Medical University-Shuang Ho Hospital
Community Medicine Research Centre and Institute of Public Health
National Yang Ming University
Taipei
Taiwan


Po-Wen Ku
Graduate Institute of Sports and Health, National Changhua University of Education
National Yang Ming University
Taipei
Taiwan


Da-Chen Chu
Department of Neurosurgery, Taipei City Hospital
Community Medicine Research Centre and Institute of Public Health
National Yang Ming University
Taipei
Taiwan


Tsan-Hon Liou
Department of Physical Medicine and Rehabilitation
Taipei Medical University-Shuang Ho Hospital
Taipei
Taiwan


Pesus Chou
Community Medicine Research Centre and Institute of Public Health
National Yang Ming University
Taipei
Taiwan


Justina Costandi
Department of Medicine, Graduate Department of Medical Sciences
Henderson Research Centre, McMaster University, Hamilton
Graduate Department of Medical Sciences
Ontario
Canada


Michelle Melone
Department of Medicine, Henderson Research Centre
McMaster University, Hamilton
Ontario
Canada


Shirya Rashid
Department of Medicine, Graduate Department of Medical Sciences
Henderson Research Centre, McMaster University
Graduate Department of Medical Sciences
McMaster University, Hamilton
Ontario
Canada


Silvia de Barros-Mazon
Department of Clinical Pathology
Faculty of Medical Sciences, University of Campinas (UNICAMP)
Sao Paulo
Brazil


Daniela Miguel Marin
Department of Internal Medicine
Faculty of Medical Sciences, University of Campinas (UNICAMP)
Sao Paulo
Brazil


Puzzi de Carvalho Camila
Department of Internal Medicine
Faculty of Medical Sciences, University of Campinas (UNICAMP)
Sao Paulo
Brazil


Sarah Monte Alegre
Department of Internal Medicine
Faculty of Medical Sciences, University of Campinas (UNICAMP)
Sao Paulo
Brazil


Mohannad Kusti
Department of Bariatric and Advanced Laparoscopic Surgery
Preston Memorial Hospital, Kingwood
West Virginia
USA


Forrest Olgers
Department of Bariatric and Advanced Laparoscopic Surgery
Preston Memorial Hospital, Kingwood
West Virginia
USA


Ehab Akkary
Department of Bariatric and Advanced Laparoscopic Surgery
Preston Memorial Hospital, Kingwood
West Virginia
USA


Kyoungmi Kim
Division of Biostatistics
University of California Davis School of Medicine and Technology and Innovation, Solae
St. Louis
MO
USA


Stanislav O. Zakharkin
Division of Biostatistics
University of California Davis School of Medicine and Technology and Innovation, Solae
St. Louis
MO
USA


Cynthia Arbeeny
Vice President Endocrine and Metabolic Diseases
Genzyme Corporation, 49 New York Ave.
Framingham
MA , 01701-9322
USA


Christian Carpéné
INSERM, U858 Institut de Médecine Moléculaire de Rangueil
Université de Toulouse III
UPS, IFR 150
Toulouse
France


Zsuzsa Iffiú-Soltész
Université de Toulouse III
UPS, IFR 150
Toulouse
France
/
Department of Pharmacodynamics
Semmelweis University
Budapest
Hungary


Cintia Curioni
Departamento de Nutrição Social
Universidade do Estado do Rio de Janeiro
Rua S Francisco Xavier, 524 – Maracanã
Rio de Janeiro
RJ, 20550-900
Brazil


Cintia Azara
Faculdade Arthur Sá Earp Neto
Av. Barão do Rio Branco 1003
Centro Petrópolis
RJ, 25680-120
Brazil


Jane Capelli
Universidade Federal do Rio de Janeiro, Campus Macaé – Curso de Nutrição
Rua Aluísio da Silva Gomes, 50
Granja dos Cavaleiros
Macaé
RJ, 27930-560
Brazil


Taesun Park
Department of Food and Nutrition
Yonsei University, 262 Seongsanno, Seodaemun-gu
University of Udine
Seoul, 120-749
Republic of Korea


Yunjung Kim
Department of Food and Nutrition
Yonsei University, University of Udine
262 Seongsanno, Seodaemun-gu
Seoul, 120-749
Republic of Korea


Caroline Reid
Department of Kinesiology and Health Science, York University
4700 Keele Street, M3J 1P3, 503-10 Navy Wharf Court
Toronto, M5V 3V2
Ontario
Canada


Caroline Davis
Department of Kinesiology and Health Science, York University
4700 Keele Street M3J 1P3, 503-10 Navy Wharf Court
Toronto, M5V 3V2
Ontario
Canada


Gildardo Rivera
Departamento de Farmacia y Química Medicinal
Unidad Académica Multidisciplinaria Reynosa Aztlán
Universidad Autónoma de Tamaulipas
Calle 16 y Lago de Chápala, s/n
Reynosa, 88740
México


Antonio Monge
Unidad de Investigación y Desarrollo de Medicamentos
Centro de Investigación en Farmacobiología Aplicada (CIFA)
Universidad de Navarra, Calle Irunlarrea, s/n
Pamplona, 31008
España


Virgilio Bocanegra-Garcia
Departamento de Farmacia y Química Medicinal
Unidad Académica Multidisciplinaria Reynosa Aztlán
Universidad Autónoma de Tamaulipas
Calle 16 y Lago de Chápala, s/n
Reynosa, 88740
México


Laurence Hoareau
Groupe d’Etude sur l’Inflammation Chronique et l’Obésité (GEICO), Plateforme CYROI
Université de La Réunion, 2 rue Maxime Rivière
Sainte Clotilde, 97490
France


Karima Bencharif
Groupe d’Etude sur l’Inflammation Chronique et l’Obésité (GEICO)
Plateforme CYROI - Université de La Réunion
2 rue Maxime Rivière
Sainte Clotilde, 97490
France


Régis Roche
Groupe d’Etude sur l’Inflammation Chronique et l’Obésité (GEICO)
Plateforme CYROI - Université de La Réunion
2 rue Maxime Rivière
Sainte Clotilde, 97490
France


Andreas Stengel
CURE: Digestive Diseases Research Center and Center for Neurovisceral Sciences and Women's Health
Digestive Diseases Division, David Geffen School of Medicine at UCLA
VA Greater Los Angeles Healthcare System
Los Angeles
California
USA


Miriam Goebel
CURE: Digestive Diseases Research Center and Center for Neurovisceral Sciences and Women's Health
Digestive Diseases Division, David Geffen School of Medicine at UCLA
VA Greater Los Angeles Healthcare System
Los Angeles
California
USA


Yvette Taché
CURE: Digestive Diseases Research Center and Center for Neurovisceral Sciences and Women's Health
Digestive Diseases Division, David Geffen School of Medicine at UCLA
VA Greater Los Angeles Healthcare System
Los Angeles
California
USA


Andreas D. Flouris
FAME Laboratory, Institute of Human Performance and Rehabilitation
Centre for Research and Technology Thessaly, Karies
Trikala, 42100
Greece


Andres E. Carrillo
FAME Laboratory, Institute of Human Performance and Rehabilitation
Centre for Research and Technology Thessaly, Karies
Trikala, 42100
Greece


Giorgos S. Metsios
School of Sports, Performing Arts and Leisure, University of Wolverhampton
Walsall Campus, Gorway Road
Walsall, WS1 3BD
UK


Susan Jacob
Department of Veterans Affairs Loma Linda
Western University of Health Sciences
Pomona
CA
USA


Nhu Nguyen
Department of Veterans Affairs Loma Linda
Western University of Health Sciences
Pomona
CA
USA


Christian S. Jackson
Department of Veterans Affairs Loma Linda
Western University of Health Sciences
Pomona
CA
USA


Stewart Rendon
Department of Veterans Affairs Loma Linda
Western University of Health Sciences
Pomona
CA
USA




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