Editors: Atta-ur-Rahman, M. Iqbal Choudhary

Frontiers in Anti-infective Drug Discovery

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $213
Printed Copy: US $191
Library License: US $176
ISSN: 2451-9162 (Print)
ISSN: 1879-663X (Online)
ISBN: 978-1-60805-583-8 (Print)
ISBN: 978-1-60805-158-8 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080515881100101

Introduction

“Frontiers in Anti-Infective Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Infective drug design and discovery. Each volume is devoted to the major advances in Anti-Infective drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Indexed in: Scopus, Book Citation Index, Science Edition, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO.

Preface

- Pp. i
Atta-ur-Rahman and M. Iqbal Choudhary
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Contributors

- Pp. ii-vi (3)
Bentham Science Publishers
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Strategies for Effective Naked-DNA Vaccination Against Infectious Diseases

- Pp. 1-16 (16)
Pieranna Chiarella, Emanuela Massi, Mariangela De Robertis, Vito M. Fazio and Emanuela Signori

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Light Activated Compounds as Patented Antimicrobial Agents

- Pp. 17-48 (32)
David Andrew Phoenix and Frederick Harris

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Proteases and Kinases: Attractive Targets for Combating Infectious Diseases

- Pp. 49-69 (21)
Mona Arabshahi, Usha Bughani, Surya N. Vangapandu, Ritu Aneja, Ramesh Chandra, Daniel Kalman and Harish Joshi

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Antibacterial Therapy in the Elderly

- Pp. 70-82 (13)
Ayman M. Noreddin and Walid F. El-Khatib

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SARS Coronavirus Anti-Infectives

- Pp. 83-106 (24)
Tommy R. Tong

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Probiotics as Drugs Against Human Gastrointestinal Pathogens

- Pp. 107-123 (17)
Yolanda Sanz, Inmaculada Nadal and Ester Sanchez

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Insights into the Treatment of Helicobacter pylori Infection

- Pp. 124-137 (14)
Campo Salvatore Maria Antonio, Hassan Cesare, Burza Maria Antonietta, Ridola Lorenzo, Cristofari Francesca, Morini Sergio and Zullo

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Inhibitors of Bacterial Efflux Pumps as Adjuvants in Antibacterial Therapy and Diagnostic Tools for Detection of Resistance by E

- Pp. 138-175 (38)
Francoise Van Bambeke, Jean-Marie Pages and Ving J. Lee

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Drugs Candidates in Advanced Clinical Trials Against Tuberculosis

- Pp. 176-201 (26)
Marcus Vinicius Nora de Souza, Marcelle de Lima Ferreira and Raoni Schroeder B. Goncalves

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Drug Effects on Drug Targets: Inhibition of Enzymes by Neuroleptics, Antimycotics, Antibiotics and Other Drugs on Human Pathogen

- Pp. 202-226 (25)
Raul N. Ondarza

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Macrophage Inflammatory Protein 1 and CCR5 as Potential Therapeutic Targets for HIV Infection and Acquired Immunodeficiency Synd

- Pp. 227-237 (11)
Tsuyoshi Kasama, Ryo Takahashi, Michihito Sato and Kuninobu Wakabayashi
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Small-Molecule Inhibitors of Raf for Treatment of Malignant Diseases

- Pp. 238-250 (13)
Li Li, Shuhong Wu, Wei Guo and Bingliang Fang
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Tigecycline: A New Treatment Choice Against Acinetobacter baumannii

- Pp. 251-260 (10)
Virginia Boso-Ribelles, Eva Roma-Sanchez, Jorge Carmena, Cristina Caceres and Daniel Bautista

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Cefepime and its Role in Pediatric Infections

- Pp. 261-268 (8)
Sukhbir K. Shahid

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Antibacterial Properties of Organosulfur Anti-Infectives: A Review of Patent Literature 1999-2009

- Pp. 269-278 (10)
Monika I. Konaklieva and Balbina J. Plotkin

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A Review of the Carbapenems in Clinical Use and Clinical Trials

- Pp. 279-293 (15)
Tze Shien Lo, Justin M. Welch, Augusto M. Alonto and Eileen Anne R. Vicaldo-Alonto

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Anti-Infective Quinone Derivatives of Recent Patents

- Pp. 294-322 (29)
Junko Koyama

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Targets and Patented Drugs for Chemotherapy of Chagas Disease

- Pp. 323-408 (86)
Vilma G. Duschak and Alicia S. Couto

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Recent Patents on Development of Nucleic Acid-Based Antiviral Drugs against Seasonal and Pandemic Influenza Virus Infections

- Pp. 409-425 (17)
Edward G. Saravolac and Jonathan P. Wong

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Author Index to Volume 1

- Pp. 426- (1)
Atta-ur-Rahman and M. Iqbal Choudhary
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