Editor: Atta-ur-Rahman / Khurshid Zaman

Topics in Anti-Cancer Research

Volume 2

eBook: US $129 Special Offer (PDF + Printed Copy): US $232
Printed Copy: US $168
Library License: US $516
ISSN: 2468-5860 (Print)
ISSN: 2213-3585 (Online)
ISBN: 978-1-60805-139-7 (Print)
ISBN: 978-1-60805-136-6 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080513661130201

Introduction

This is the second volume of the Patent eBook Series titled Topics in Anti-Cancer Research. The eBook includes updated chapters on topics relevant to contemporary cancer research published in the journal, Recent Patents on Anti-Cancer Drug Discovery.

This volume covers scientific and patented novel chemotherapeutic agents and drugs for metastatic castration-resistant prostate cancer and Ras/ Raf /MEK/ERK pathway, P1K, AKT and mTORC1/2 inhibitors, ATPase inhibitors for cancer therapy, and sphingomyelin biosynthesis which regulates cancer cell death and growth.

Other chapters also explain research on biochemical regulation i.e. cell cycle and energy metabolism, the role of genetic variations of FcγRs gamma receptors in monoclonal antibody based anti-cancer therapy and effectiveness of antiangiogenic therapy, endogenous angiogenesis inhibitors and anti-angiogenic drugs for the treatment of renal cell carcinoma, prevention of cancer by ribonucleotide reductase, anticancer activity of Erlotinib in glioblastoma and the mechanisms of action of nanodrugs and nano-sized camptothecin drugs in cancer chemotherapy. The volume also covers recent studies in the field of onconutrition. The broad range of topics covered in this second volume will be of immense interest to clinicians, scientists and R&D experts seeking new targets for the prevention of cancer, novel oncogenic biomarkers, and methods for cancer therapy.

Indexed in: Book Citation Index, Science Edition, Chemical Abstracts, BIOSIS Previews, EBSCO, Ulrich's Periodicals Directory.

Foreword

- Pp. i-iii (3)
Atta-ur-Rahman and Khurshid Zaman
Download Free

List of Contributors

- Pp. iv-v (2)
Atta-ur-Rahman and Khurshid Zaman
Download Free

Introduction

- Pp. vi
Atta-ur-Rahman and Khurshid Zaman
Download Free

Emerging Research and Therapeutic Strategies for Castration-Resistant Prostate Cancer

- Pp. 3-34 (32)
Tomoaki Tanaka and Tatsuya Nakatani

PDF Price: $30

View Abstract Purchase Chapter

Sphingomyelin Biosynthesis Modulates Cancer Cell Death and Growth

- Pp. 35-62 (28)
Elodie Lafont, Kazuyuki Kitatani, Toshiro Okazaki and Bruno Ségui

PDF Price: $30

View Abstract Purchase Chapter

The Therapeutic Promise of Anti-Cancer Drugs Against the Ras/Raf/MEK/ERK Pathway

- Pp. 63-94 (32)
Erin K. Crane and Kwong-Kwok Wong
View Abstract Download Free

Recent Developments in Anticancer Agents Targeting PI3K, AKT and mTORC1/2

- Pp. 95-196 (102)
Irene Brana, Sara De Dosso, Rodrigo Dienstmann, Jordi Rodon, Josep Tabernero and Ben Markman

PDF Price: $30

View Abstract Purchase Chapter

Cell Cycle and Energy Metabolism in Tumor Cells: Strategies for Drug Therapy

- Pp. 197-230 (34)
Nivea D. Amoêdo, Tatiana El-Bacha Porto, Mariana F. Rodrigues and Franklin D. Rumjanek

PDF Price: $30

View Abstract Purchase Chapter

V-ATPase Inhibitors in Cancer Therapy: Targeting Intraorganellar Acidification

- Pp. 231-256 (26)
Agustín Hernández, Gloria Serrano-Bueno, Rosana Herrera-Palau, José R. Pérez-Castiñeira and Aurelio Serrano

PDF Price: $30

View Abstract Purchase Chapter

Insights into the Role of Fc Gamma Receptors (FcγRs) Genetic Variations in Monoclonal Antibody-Based Anti-cancer Therapy

- Pp. 257-278 (22)
Fabio Concetti and Valerio Napolioni

PDF Price: $30

View Abstract Purchase Chapter

Angiogenesis: Therapeutic Target in Renal Cell Carcinoma

- Pp. 279-298 (20)
Manisha Singh, Sudip Nanda, Santo Longo and Shree G. Sharma

PDF Price: $30

View Abstract Purchase Chapter

Anti-Angiogenic Therapy for Cancer: Past, Present and Future

- Pp. 299-319 (21)
Boel De Paepe

PDF Price: $30

View Abstract Purchase Chapter

Paradigm Shift in the Therapeutic Potential of Endogenous Angiogenesis Inhibitors for Cancer Therapy: Historical Perspective and Future Direction

- Pp. 320-362 (43)
Mohanraj Dhanabal and Natarajan Sethuraman

PDF Price: $30

View Abstract Purchase Chapter

Ribonucleotide Reductase as a Target to Control Cancer Proliferation

- Pp. 363-406 (44)
Nuno M.F.S.A. Cerqueira, Narayana S.H.N. Moorthy, Pedro A. Fernandes and Maria J. Ramos

PDF Price: $30

View Abstract Purchase Chapter

Enhancing the Anticancer Activity of Erlotinib in Glioblastoma

- Pp. 407-436 (30)
Georg Karpel-Massler, Christian R. Wirtz and Marc-Eric Halatsch

PDF Price: $30

View Abstract Purchase Chapter

Nanodrugs: Magic Bullets in Cancer Chemotherapy

- Pp. 437-494 (58)
Kishwar Saleem, Waseem A. Wani, Ashanul Haque, Archana Milhotra and Imran Ali

PDF Price: $30

View Abstract Purchase Chapter

Chemotherapy of Nano-Sized Camptothecin-Derived Drugs

- Pp. 495-521 (27)
Nguyen-Van Cuong, Chi-Hui Guo and Ming-Fa Hsieh

PDF Price: $30

View Abstract Purchase Chapter

Onconutrition: Redox Chemoprevention by Functional Biomolecules and Biomarker Assessment

- Pp. 522-552 (31)
María D. Defagó and Elio A. Soria

PDF Price: $30

View Abstract Purchase Chapter

Author Index

- Pp. 553
Atta-ur Rahman and Khurshid Zaman
Download Free

Index

- Pp. 554-576 (23)
Atta-ur Rahman and Khurshid Zaman
Download Free

RELATED BOOKS

.Avastin and Malignant Gliomas .
.Cutting Edge Therapies for Cancer in the 21 Century.
.Cancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune-Based Therapies and Developing Clinical Trials.
.Systems Biology in Cancer Immunotherapy.