Editor: John A. Dangerfield

GPI Membrane Anchors-The Much Needed Link

eBook: US $49 Special Offer (PDF + Printed Copy): US $113
Printed Copy: US $89
Library License: US $196
ISBN: 978-1-60805-375-9 (Print)
ISBN: 978-1-60805-123-6 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080512361100101

Introduction

This Ebook aims to review basic understandings and give current opinions about several important aspects of glycosylphosphatidylinositol-anchored (GPI) protein biology from leading experts in this exciting and emerging field. The scope ranges from micro-domain localization and signaling to proteomics aspects, biophysical behavior through trans-cellular mobility to chemical synthesis of GPI mimics and finally modification of multi-scaled membrane surfaces and potential medical and biotech uses. The applied slant makes it very useful to the current state of knowledge. It is hoped that it will prove to be of considerable interest to students and researchers in this field.

Foreword

- Pp. i
Brian Salmons
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Preface

- Pp. ii
John A. Dangerfield and Christoph Metzner
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Contributors

- Pp. iii-iv (2)
John A. Dangerfield and Christoph Metzner
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GPI-Anchored Proteins and Their Cellular Surroundings: Signalling, Function and Medical Implications of Membrane Microdomains

- Pp. 1-18 (18)
Vera Michel, David W.L. Ma and Marica Bakovic

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Trans-Cellular Mobility of GPI-Anchored Proteins

- Pp. 19-33 (15)
Barbara Viljetic, Marija Heffer-Lauc and Gordan Lauc

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GPI-Anchored Proteins: Biophysical Behaviour and Cleavage by Pi-Specific Phospholipases

- Pp. 34-52 (19)
Frances. J. Sharom

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Proteomic Approaches for GPI-Anchored Protein Analysis

- Pp. 53-63 (11)
Miren J. Omaetxebarria and Felix Elortza

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Chemical Synthesis, Modification and Mimicry of the GPI Anchor

- Pp. 64-82 (19)
Martin J. Lear, Bastien Reux and Karthik Sekar

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Surface Engineering of Biomembranes with GPI-Anchored Proteins and its Applications

- Pp. 83-97 (15)
Christoph Metzner, Daniel F. Legler and John A. Dangerfield

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Glossary

- Pp. 98-102 (5)
John A. Dangerfield and Christoph Metzner

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Index

- Pp. 103-104 (2)
John A. Dangerfield and Christoph Metzner
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