Editors: Antonio Teixeira, Marina Vinaud, Ana Maria Castro

Emerging Chagas Disease

eBook: US $89 Special Offer (PDF + Printed Copy): US $176
Printed Copy: US $131
Library License: US $356
ISBN: 978-1-60805-569-2 (Print)
ISBN: 978-1-60805-041-3 (Online)
Year of Publication: 2009
DOI: 10.2174/97816080504131090101

Introduction

The book focuses on a global problem challenging the health systems. Trypanosoma cruzi infections are transmitted by cone-nosed triatomine bugs, by blood transfusion and congenitally from mothers to their offspring. The American Trypanosomiasis affects 20 million people; among them a significant parcel (< 1/3) will develop Chagas disease in the heart and digestive tract, where the immune system effector cells destroy target host cells. Genotype modifications resulting from transfer of minicircle sequence kDNA from the parasite into the host´s genome may explain the autoimmune pathogenesis of the disease. The book discusses various aspects of this disease and should be of interest to readers who wish to keep abreast of the developments in this field.

Contributors

Editor(s):
Antonio Teixeira
University of Brasilia
Brazil


Marina Vinaud
Universidade Federal de Goiás
Brazil


Ana Maria Castro
Universidade Federal de Goiás
Brazil




Contributor(s):
João Carlos Pinto Dias M.D., Ph.D.
Senior Researcher, Centro de Pesquisas René Rachou
Instituto Oswaldo Cruz
Belo Horizonte
Brasil


Christopher John Schofield Ph.D.
Honorary Senior Lecturer, ECLAT Coordinator
London School of Tropical Medicine
UK


Antonio Teixeira M.D., Ph.D.
Professor, Chagas Disease Multidisciplinary Research Laboratory
Faculty of Medicine
University of Brasilia, Federal District
Brasilia, 70.910-900
Brazil


Rubens Nascimento Ph.D.
Researcher, Chagas Disease Multidisciplinary Research Laboratory
Federal District
Brasilia, 70.910-900
Brazil


Nancy R. Sturm Ph.D.
Associate Researcher, Department of Microbiology
Immunology & Molecular Genetics
University of California at Los Angeles
California, 90095-1489
USA


Ana Maria Castro Ph.D.
Associate Professor, Department of Microbiology
Immunology, Parasitology and Pathology
Tropical Pathology and Public Helath Institute , Universidade Federal de Goiás
Goiânia, 74.605-050
Brazil


Marina Claude Vinaud Ph.D.
Associate Professor, Department of Microbiology
Immunology, Parasitology and Pathology, Tropical Pathology and Public Helath Institute
Universidade Federal de Goiás
Goiânia, 74.605-050
Brazil


Lileia Diotaiuti M.D., Ph.D.
Senior Researcher, Centro de Pesquisas René Rachou
Instituto Oswaldo Cruz, Belo Horizonte
Brasil


Wanderley de Souza M.D., Ph.D.
Professor, Laboratório de Ultraestrutura Celular Hertha Meyer,
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro
CCS-Bloco G, Ilha do Fundão, Rio de Janeiro
Rio de Janeiro, 21941-900
Brasil


Kildare Miranda Ph.D.
Associate Professor, Laboratório de Ultraestrutura Celular Hertha Meyer,
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro
CCS-Bloco G, Ilha do Fundão, Rio de Janeiro
Rio de Janeiro, 21941-900
Brasil


Narcisa Leal Cunha e Silva Ph.D.
Associate Professor, Laboratório de Ultraestrutura Celular Hertha Meyer,
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro
CCS-Bloco G, Ilha do Fundão, Rio de Janeiro
Rio de Janeiro, 21941-900
Brasil


Thaïs Souto-Padrón Ph.D.
Professor, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro,
Ilha do Fundão
Rio de Janeiro, 21941-9000
Brasil


David A Campbell Ph.D.
Professor, Department of Microbiology
Immunology & Molecular Genetics, University of California
Los Angeles
California, 90095-1489
USA


David M. Engman M.D., Ph.D.
Professor, Departments of Pathology and Microbiology-Immunology
Northwestern University
Chicago
Illinois, 60611
USA


Conrad L. Epting M.D.
Assistant Professor, Department of Pediatrics
Chicago
Illinois, 60611
USA


Kevin M. Bonney B.S.
Researcher, Departments of Pathology and Microbiology-Immunology
Chicago
Illinois, 60611
USA


Maurício Martins Rodrigues M.D., Ph.D.
Associate Professor, Departamento de Microbiologia
Imunologia e Parasitologia
Universidade Federal de São Paulo-Escola Paulista de Medicina
São Paulo, 04044-010
Brazil


Bruna Cunha de Alencar
Research Assistant, Departamento de Microbiologia, Imunologia e Parasitologia
Universidade Federal de São Paulo-Escola Paulista de Medicina
São Paulo, 04044-010
Brazil


José Ronnie Vasconcelos Ph.D.
Research Assistant, Departemento de Imunologia
Instituto de Ciências Biomédicas, Univesidade de São Paulo
SP, 05508-900
Brasil


Fernando Pimentel
Research Assistant, Chagas Disease Multidisciplinary Research Laboratory
Faculty of Medicine, University of Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Ciro Cordeiro
Research Assistant, Chagas Disease Multidisciplinary Research Laboratory
University of Brasilia
Faculty of Medicine, Federal District
Brasilia, 70.910-900
Brazil


Nadjar Nitz Ph.D.
Associate Professor, Chagas Disease Multidisciplinary Research Laboratory
Faculty of Medicine, University of Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Mariana M. Hecht Ph.D.
Assistant Professor, Chagas Disease Multidisciplinary Research Laboraqtory
Faculty of Medicine, University of Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Liana Lauria-Pires M.D., Ph.D.
Associate Professor, Chagas Disease Multidisciplinary Research Laboraqtory
Faculty of Medicine, University of Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Ana de Cassia Rosa Ph.D.
Researcher, Chagas Disease Multidisciplinary Research Laboraqtory
Faculty of Medicine, University of Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Cleudson Nery de Castro M.D., Ph.D.
Associate Professor, Núcleo de Medicina Tropical da Universidade de Brasilia
Federal District
Brasilia, 70.910-900
Brazil


Izabela M. Dourado Bastos Ph.D.
Associate Professor, Laboratory of Host-Parasite Interface
Institute of Biology/Faculty of Medicine
The University of Brasília
Brasília, 70910-900
Brazil


David Neves Ph.D.
Research Assistant, Laboratory of Host-Parasite Interface
Institute of Biology/Faculty of Medicine
The University of Brasília
Brasília, 70910-900
Brazil


Meire M. Lima Ph.D.
Research Assistant, Laboratory of Host-Parasite Interface
Institute of Biology/Faculty of Medicine
The University of Brasília
Brasília, 70910-900
Brazil


Jaime M. Santana, Ph.D.
Associate Professor, Laboratory of Host-Parasite Interface
Institute of Biology/Faculty of Medicine
The University of Brasília
Brasília, 70910-900
Brazil


Clever Gomes Ph.D.
Research Assistant, Chagas Disease Multidisciplinary Research Laboratory
Faculty of Medicine, University of Brasília
Federal District
Brasília, 70910-900
Brazil


Silene Lozzi Ph.D.
Associate Professor, Department of Genetics and Morphology
Institute of Biology, University of Brasilia
Federal District
Brasília, 70910-900
Brazil


Pedro Monteiro, Ph.D.
Associate Professor, Department of Nursery, Faculty of Health Sciences
University of Brasília
Federal District
Brasília, 70910-900
Brazil


Ana Bussacos Ph.D.
Research Assistant, Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine
University of Brasília
Federal District
Brasília, 70910-900
Brazil


Concepta McManus M.V.D., Ph.D.
Associate Professor, Faculty of Veterinary Medicine
University of Brasilia
Federal District
Brasília, 70910-900
Brazil


Alessandro Sousa
Research Assistant, Chagas Disease Multidisciplinary Research Laboratory
Faculty of Medicine, University of Brasilia
Federal District
Brasília, 70910-900
Brazil




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