Foreword

The design and development of biomaterials with good biocompatibility and mechanical properties to replace defective bones are of profound technological importance. Advanced nitinol alloys and polymer-based nanocomposites have potential applications as spinal and load-bearing implant biomaterials in orthopedics. The nitinol alloys exhibit superelasticity and shape memory effect. By implanting nitinol alloys into patients with severe scoliosis, the deformity can be safely corrected. Poly (ether ether ketone) nanocomposites reinforced with low loading level of carbon nanotubes display strength and stiffness closely matching those of cortical bone. This monograph provides the latest development and topics in biomedical science and engineering. Focusing exclusively on the fundamental aspects and applications of biomaterials and biomedical sciences, this authoritative reference:

• Presents the design philosophy of spinal implants for scoliosis correction;
• Introduces nitinol alloys with superelasticity and shape memory effect, and their clinical applications;
• Describes the plasma immersion ion implantation of NiTi shape memory alloys;
• Includes bioactive bone cement for orthopedic applications;
• Covers new research trends in polymer nanocomposites including nano-hydroxyapaptite/polymer and carbon nanotube/polymer biocomposites;
• Reviews the biocompatibility of electrospun nanocomposite scaffolds;
• Discusses responses of biological cells upon exposure to ionizing radiation; and Evaluates in vivo toxicity of carbon nanotubes in zebrafish embryos.

With chapters contributed by eminent scientists and surgeons in Hong Kong specializing in biophysics, biomaterials, biomedical engineering and orthopedics, this is a useful reference for scientists, biomedical engineers, medical practitioners and medical technologists